Induction of senescence in primary glioblastoma cells by serum and TGFβ

Abstract Glioblastoma is the most common type of adult brain tumour and has a median survival after diagnosis of a little more than a year. Glioblastomas have a high frequency of mutations in the TERT promoter and CDKN2A locus that are expected to render them resistant to both replicative and oncoge...

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Auteurs principaux: Ritesh Kumar, Alexander Gont, Theodore J. Perkins, Jennifer E. L. Hanson, Ian A. J. Lorimer
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/9600ca8f6ee94a838aaa5c94ff55151b
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