Neural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model

We consider the mathematical model of chemotaxis introduced by Patlak, Keller, and Segel. Aggregation and progression waves are present everywhere in the population dynamics of chemotactic cells. Aggregation originates from the chemotaxis of mobile cells, where cells are attracted to migrate to high...

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Autores principales: Sunwoo Hwang, Seongwon Lee, Hyung Ju Hwang
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Publicado: AIMS Press 2021
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spelling oai:doaj.org-article:9602e92d47e646cc9d3ee6983704e6022021-11-29T00:42:47ZNeural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model10.3934/mbe.20214211551-0018https://doaj.org/article/9602e92d47e646cc9d3ee6983704e6022021-09-01T00:00:00Zhttps://www.aimspress.com/article/doi/10.3934/mbe.2021421?viewType=HTMLhttps://doaj.org/toc/1551-0018We consider the mathematical model of chemotaxis introduced by Patlak, Keller, and Segel. Aggregation and progression waves are present everywhere in the population dynamics of chemotactic cells. Aggregation originates from the chemotaxis of mobile cells, where cells are attracted to migrate to higher concentrations of the chemical signal region produced by themselves. The neural net can be used to find the approximate solution of the PDE. We proved that the error, the difference between the actual value and the predicted value, is bound to a constant multiple of the loss we are learning. Also, the Neural Net approximation can be easily applied to the inverse problem. It was confirmed that even when the coefficient of the PDE equation was unknown, prediction with high accuracy was achieved.Sunwoo HwangSeongwon LeeHyung Ju HwangAIMS Pressarticledifferential equationapproximated solutionartificial neural networkspatlak-keller-segel equationBiotechnologyTP248.13-248.65MathematicsQA1-939ENMathematical Biosciences and Engineering, Vol 18, Iss 6, Pp 8524-8534 (2021)
institution DOAJ
collection DOAJ
language EN
topic differential equation
approximated solution
artificial neural networks
patlak-keller-segel equation
Biotechnology
TP248.13-248.65
Mathematics
QA1-939
spellingShingle differential equation
approximated solution
artificial neural networks
patlak-keller-segel equation
Biotechnology
TP248.13-248.65
Mathematics
QA1-939
Sunwoo Hwang
Seongwon Lee
Hyung Ju Hwang
Neural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model
description We consider the mathematical model of chemotaxis introduced by Patlak, Keller, and Segel. Aggregation and progression waves are present everywhere in the population dynamics of chemotactic cells. Aggregation originates from the chemotaxis of mobile cells, where cells are attracted to migrate to higher concentrations of the chemical signal region produced by themselves. The neural net can be used to find the approximate solution of the PDE. We proved that the error, the difference between the actual value and the predicted value, is bound to a constant multiple of the loss we are learning. Also, the Neural Net approximation can be easily applied to the inverse problem. It was confirmed that even when the coefficient of the PDE equation was unknown, prediction with high accuracy was achieved.
format article
author Sunwoo Hwang
Seongwon Lee
Hyung Ju Hwang
author_facet Sunwoo Hwang
Seongwon Lee
Hyung Ju Hwang
author_sort Sunwoo Hwang
title Neural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model
title_short Neural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model
title_full Neural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model
title_fullStr Neural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model
title_full_unstemmed Neural network approach to data-driven estimation of chemotactic sensitivity in the Keller-Segel model
title_sort neural network approach to data-driven estimation of chemotactic sensitivity in the keller-segel model
publisher AIMS Press
publishDate 2021
url https://doaj.org/article/9602e92d47e646cc9d3ee6983704e602
work_keys_str_mv AT sunwoohwang neuralnetworkapproachtodatadrivenestimationofchemotacticsensitivityinthekellersegelmodel
AT seongwonlee neuralnetworkapproachtodatadrivenestimationofchemotacticsensitivityinthekellersegelmodel
AT hyungjuhwang neuralnetworkapproachtodatadrivenestimationofchemotacticsensitivityinthekellersegelmodel
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