Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in Drosophila testis.
Dosage compensation equalizes X-linked expression between XY males and XX females. In male fruit flies, expression levels of the X-chromosome are increased approximately two-fold to compensate for their single X chromosome. In testis, dosage compensation is thought to cease during meiosis; however,...
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Autores principales: | Evan Witt, Zhantao Shao, Chun Hu, Henry M Krause, Li Zhao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/961087cf739e4ebf9fcb30ff8f3a887b |
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