Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes

Phage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores.

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Autores principales:	Noa Katz, Eitamar Tripto, Naor Granik, Sarah Goldberg, Orna Atar, Zohar Yakhini, Yaron Orenstein, Roee Amit
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9616667022114a1680b5c585955aa3b8
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spelling	oai:doaj.org-article:9616667022114a1680b5c585955aa3b82021-12-02T13:14:59ZOvercoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes10.1038/s41467-021-21578-62041-1723https://doaj.org/article/9616667022114a1680b5c585955aa3b82021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21578-6https://doaj.org/toc/2041-1723Phage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores.Noa KatzEitamar TriptoNaor GranikSarah GoldbergOrna AtarZohar YakhiniYaron OrensteinRoee AmitNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Noa Katz Eitamar Tripto Naor Granik Sarah Goldberg Orna Atar Zohar Yakhini Yaron Orenstein Roee Amit Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes
description	Phage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores.
format	article
author	Noa Katz Eitamar Tripto Naor Granik Sarah Goldberg Orna Atar Zohar Yakhini Yaron Orenstein Roee Amit
author_facet	Noa Katz Eitamar Tripto Naor Granik Sarah Goldberg Orna Atar Zohar Yakhini Yaron Orenstein Roee Amit
author_sort	Noa Katz
title	Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes
title_short	Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes
title_full	Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes
title_fullStr	Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes
title_full_unstemmed	Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes
title_sort	overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-rna cassettes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9616667022114a1680b5c585955aa3b8
work_keys_str_mv	AT noakatz overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes AT eitamartripto overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes AT naorgranik overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes AT sarahgoldberg overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes AT ornaatar overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes AT zoharyakhini overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes AT yaronorenstein overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes AT roeeamit overcomingthedesignbuildtestbottleneckforsynthesisofnonrepetitiveproteinrnacassettes
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Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes

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