Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India

Objectives Healthcare workers (HCWs) are at a high risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to the increased likelihood of clinical exposure during patient management. The study objective was to determine the seroprevalence of antibodies to SARS-CoV-2 and...

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Autores principales:	Pragya Sharma, Rohit Chawla, Ritika Bakshi, Sonal Saxena, Saurav Basu, Pradeep Kumar Bharti, Meera Dhuria, S. K. Singh, Panna Lal
Formato:	article
Lenguaje:	EN
Publicado:	Korea Centers for Disease Control & Prevention 2021
Materias:	communicable diseases covid-19 occupational health Special situations and conditions RC952-1245 Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/96172fb3e50f40579744e2d330120323
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spelling	oai:doaj.org-article:96172fb3e50f40579744e2d3301203232021-11-05T00:00:17ZSeroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India2210-90992210-911010.24171/j.phrp.2021.12.2.06https://doaj.org/article/96172fb3e50f40579744e2d3301203232021-04-01T00:00:00Zhttp://ophrp.org/upload/pdf/j-phrp-2021-12-2-06.pdfhttps://doaj.org/toc/2210-9099https://doaj.org/toc/2210-9110Objectives Healthcare workers (HCWs) are at a high risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to the increased likelihood of clinical exposure during patient management. The study objective was to determine the seroprevalence of antibodies to SARS-CoV-2 and its predictors among hospital employees. Methods The cross-sectional study was conducted at a teaching hospital from August 2020 to September 2020 among 1,401 employees, including 1,217 HCWs, in New Delhi, India. The serum samples were examined for immunoglobulin G (IgG) antibodies to SARS-CoV-2 using the COVID Kavach-Anti-SARS-CoV-2 IgG Antibody Detection enzyme-linked immunosorbent assay kit. Data were collected electronically using the EpiCollect mobile platform. A p < 0.05 was considered to indicate statistical significance. Results A total of 169 participants (12.1%) had detectable IgG antibodies to SARS-CoV-2. The highest seropositivity rate was observed in the administrative staff (20.1%), while it was lowest among medical doctors (5.5%, p < 0.001). Male sex and ever having lived in a containment zone were independently associated with past infection with SARS-CoV-2. Conclusion The seroprevalence of SARS-CoV-2 infection in health workers may be lower than in the general population in New Delhi. However, nonpharmaceutical interventions were not associated with a reduction in the risk of acquisition of SARS-CoV-2.Pragya SharmaRohit ChawlaRitika BakshiSonal SaxenaSaurav BasuPradeep Kumar BhartiMeera DhuriaS. K. SinghPanna LalKorea Centers for Disease Control & Preventionarticlecommunicable diseasescovid-19occupational healthSpecial situations and conditionsRC952-1245Infectious and parasitic diseasesRC109-216ENOsong Public Health and Research Perspectives, Vol 12, Iss 2, Pp 88-95 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	communicable diseases covid-19 occupational health Special situations and conditions RC952-1245 Infectious and parasitic diseases RC109-216
spellingShingle	communicable diseases covid-19 occupational health Special situations and conditions RC952-1245 Infectious and parasitic diseases RC109-216 Pragya Sharma Rohit Chawla Ritika Bakshi Sonal Saxena Saurav Basu Pradeep Kumar Bharti Meera Dhuria S. K. Singh Panna Lal Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
description	Objectives Healthcare workers (HCWs) are at a high risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to the increased likelihood of clinical exposure during patient management. The study objective was to determine the seroprevalence of antibodies to SARS-CoV-2 and its predictors among hospital employees. Methods The cross-sectional study was conducted at a teaching hospital from August 2020 to September 2020 among 1,401 employees, including 1,217 HCWs, in New Delhi, India. The serum samples were examined for immunoglobulin G (IgG) antibodies to SARS-CoV-2 using the COVID Kavach-Anti-SARS-CoV-2 IgG Antibody Detection enzyme-linked immunosorbent assay kit. Data were collected electronically using the EpiCollect mobile platform. A p < 0.05 was considered to indicate statistical significance. Results A total of 169 participants (12.1%) had detectable IgG antibodies to SARS-CoV-2. The highest seropositivity rate was observed in the administrative staff (20.1%), while it was lowest among medical doctors (5.5%, p < 0.001). Male sex and ever having lived in a containment zone were independently associated with past infection with SARS-CoV-2. Conclusion The seroprevalence of SARS-CoV-2 infection in health workers may be lower than in the general population in New Delhi. However, nonpharmaceutical interventions were not associated with a reduction in the risk of acquisition of SARS-CoV-2.
format	article
author	Pragya Sharma Rohit Chawla Ritika Bakshi Sonal Saxena Saurav Basu Pradeep Kumar Bharti Meera Dhuria S. K. Singh Panna Lal
author_facet	Pragya Sharma Rohit Chawla Ritika Bakshi Sonal Saxena Saurav Basu Pradeep Kumar Bharti Meera Dhuria S. K. Singh Panna Lal
author_sort	Pragya Sharma
title	Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
title_short	Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
title_full	Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
title_fullStr	Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
title_full_unstemmed	Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
title_sort	seroprevalence of antibodies to sars-cov-2 and predictors of seropositivity among employees of a teaching hospital in new delhi, india
publisher	Korea Centers for Disease Control & Prevention
publishDate	2021
url	https://doaj.org/article/96172fb3e50f40579744e2d330120323
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Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India

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