Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant

QR Code

Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant

Abstract The huge worldwide demand for vaccines targeting SARS-CoV-2 has necessitated the continued development of novel improved formulations capable of reducing the burden of the COVID-19 pandemic. Herein, we evaluated novel protein subunit vaccine formulations containing a resistin-trimerized spi...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Bassel Akache, Tyler M. Renner, Anh Tran, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Diana Duque, Julie Haukenfrers, Martin A. Rossotti, Francis Gaudreault, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wangxue Chen, Christian Gervais, Matthew Stuible, Lakshmi Krishnan, Yves Durocher, Michael J. McCluskie
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/9618e29b6e8e4f74b75065bea762626c
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

REINTERPRETATION OF THE FIRST STEP OF THE SEQUENTIAL EXTRACTION PROPOSED BY THE SMT
par: ROCCO,M, et autres
Publié: (2009)

Age factors: A view of the effect on SLA
par: Suhaimi Suhaimi
Publié: (2017)

Epsin and Sla2 form assemblies through phospholipid interfaces
par: Maria M. Garcia-Alai, et autres
Publié: (2018)

Modeling the Structural Response of Reinforced Glass Beams using an SLA Scheme
par: C. Louter, et autres
Publié: (2010)

Leveling Out the Effect of Sample Runouts on Wear when Testing on the SMT-1 Friction Machine
par: Pogonyshev V.A., et autres
Publié: (2021)

NA-SMT: A Network-Assisted Service Message Transmission Protocol for Reliable IoV Communications
par: Mohammad Zubair Khan, et autres
Publié: (2021)

Associations of Serum Resistin With the Severity and Prognosis in Patients With Community-Acquired Pneumonia
par: Chun-Mei Feng, et autres
Publié: (2021)

Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)—Peptide Tetramers
par: Wenqiang Sun, et autres
Publié: (2021)

Osteoclasts May Affect Glucose Uptake-Related Insulin Resistance by Secreting Resistin
par: Li X, et autres
Publié: (2021)

Physical activity increases the resistin concentration in hemodialyzed patients without metabolic syndrome
par: Hornik B, et autres
Publié: (2018)

Chronic features of allergic asthma are enhanced in the absence of resistin-like molecule-beta
par: Kim S. LeMessurier, et autres
Publié: (2018)

Developments in SLA and L2 Research on Psychological and Emotional Factors: A Bird’s-eye View
par: Larisa Nikitina
Publié: (2021)

Serum resistin, cardiovascular disease and all-cause mortality in patients with type 2 diabetes.
par: Claudia Menzaghi, et autres
Publié: (2014)

Critical Role of Zur and SmtB in Zinc Homeostasis of <named-content content-type="genus-species">Mycobacterium smegmatis</named-content>
par: Elke Goethe, et autres
Publié: (2020)

A comparative analysis of SLA-DRB1 genetic diversity in Colombian (creoles and commercial line) and worldwide swine populations
par: Carmen Teresa Celis-Giraldo, et autres
Publié: (2021)

Palmitic acid promotes resistin-induced insulin resistance and inflammation in SH-SY5Y human neuroblastoma
par: Hamza Amine, et autres
Publié: (2021)

Transcription of human resistin gene involves an interaction of Sp1 with peroxisome proliferator-activating receptor gamma (PPARgamma).
par: Anil K Singh, et autres
Publié: (2010)

A Deep Neural Network-Based Multi-Label Classifier for SLA Violation Prediction in a Latency Sensitive NFV Application
par: Nikita Jalodia, et autres
Publié: (2021)

Aesthetic Outcomes of Early Occlusal Loaded SLA Dental Implants with Hydroxyl Ion Modified Surface—A 12 Months Prospective Study
par: Maciej Krawiec, et autres
Publié: (2021)

Critical Role of Etching Parameters in the Evolution of Nano Micro SLA Surface on the Ti6Al4V Alloy Dental Implants
par: Pankaj Chauhan, et autres
Publié: (2021)

Porcine Epidemic Diarrhea Virus Envelope Protein Blocks SLA-DR Expression in Barrow-Derived Dendritic Cells by Inhibiting Promoters Activation
par: Jie Wang, et autres
Publié: (2021)

Serum resistin is causally related to mortality risk in patients with type 2 diabetes: preliminary evidences from genetic data
par: Andrea Fontana, et autres
Publié: (2017)

Obesity, adipocyte hypertrophy, fasting glucose, and resistin are potential contributors to nonalcoholic fatty liver disease in South Asian women
par: Albracht-Schulte K, et autres
Publié: (2019)

Resistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis
par: Ashleigh M. Philp, et autres
Publié: (2017)

Publisher Correction: Palmitic acid promotes resistin‑induced insulin resistance and inflammation in SH‑SY5Y human neuroblastoma
par: Hamza Amine, et autres
Publié: (2021)

Expression of resistin, CXCR3, IP-10, CCR5 and MIP-1α in obese patients with different severity of asthma
par: Rojas-Dotor,Sara, et autres
Publié: (2013)

Determination of the composition of heterogeneous binder solutions by surface plasmon resonance biosensing
par: Jimmy Gaudreault, et autres
Publié: (2021)

The Association Between Insulin Resistance, Leptin, and Resistin and Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients with Different Body Mass Indexes
par: Huang J, et autres
Publié: (2021)

Evaluation of adiponectin and resistin levels in gingival crevicular fluid in patients with chronic periodontitis before and after treatment: A clinico-biochemical study
par: P Fairlin, et autres
Publié: (2021)

On the Use of Surface Plasmon Resonance-Based Biosensors for Advanced Bioprocess Monitoring
par: Jimmy Gaudreault, et autres
Publié: (2021)

Comments on: “Case reports and research productivity among Syrian medical students: Review, reality, and suggested solutions”
par: Bassel Atassi
Publié: (2016)

Levetiracetam in the treatment of epilepsy
par: Bassel Abou-Khalil
Publié: (2008)

The electoral implications of uncivil and intolerant rhetoric in American politics
par: Bryan T. Gervais
Publié: (2021)

Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins
par: Maryam Hojjat Jodaylami, et autres
Publié: (2021)

Author Correction: Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins
par: Maryam Hojjat Jodaylami, et autres
Publié: (2021)

Effect of surface organic coatings of cellulose nanocrystals on the viability of mammalian cell lines
par: Jimenez AS, et autres
Publié: (2017)

Diabetes and tuberculosis interaction in Kazakhstan
par: A. Aifah, et autres
Publié: (2016)

Understanding temperature effects on recruitment in the context of trophic mismatch
par: T. Régnier, et autres
Publié: (2019)

Breastfeeding Knowledge and Behavior Among Women Visiting a Tertiary Care Center in India: A Cross-Sectional Survey
par: Priya Sultania, et autres
Publié: (2019)

Avicenna Journal of Medicine: Reviving fading legacy
par: Mohammad Arabi, et autres
Publié: (2011)