METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME

Objectives: To evaluate the pediatric patients with renal calculi in terms of bio-metabolic profile. Study Design: Cross sectional study. Place and Duration of Study: Department of pediatric nephrology the Children’s Hospital and the Institute of Child Health Lahore over a period of 10 mont...

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Autores principales:	Iram Naz, Farkhanda Hafeez
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	distal renal tubular acidosis hypercalciuria hypocitraturia metabolic workup Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/961d17e6de3545de90b9809a86c53129
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spelling	oai:doaj.org-article:961d17e6de3545de90b9809a86c531292021-11-26T03:41:10ZMETABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME0030-96482411-8842https://doaj.org/article/961d17e6de3545de90b9809a86c531292018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2570/2106https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objectives: To evaluate the pediatric patients with renal calculi in terms of bio-metabolic profile. Study Design: Cross sectional study. Place and Duration of Study: Department of pediatric nephrology the Children’s Hospital and the Institute of Child Health Lahore over a period of 10 months from Nov 2016 to Sep 2017. Material and Methods: A total 85 patients with urolithiasis up to the age of 14 years were enrolled for study. Structured history and tailored investigations were collected from all the patients. Results of the physical examination, blood chemistry, and urinary excretion of metabolites (urinary calcium, citrate, magnesium and oxalate) were recorded. Results: Out of 85 patients; 65% were males and 35% were females (2:1); mean age at presentation was 8.15 ± 5.04 years. Hypertension was documented in 57% patients. Mean level of urea and creatinine was 73.02 ± 59mg/dl and 4.435 ± 4.024mg/dl respectively. Vitamin D level was 37 ± 15.6ng/ml while serum PTH level was 51.2941 ± 26.067pg/l. Serum calcium and phosphorus was 8.54 ± 1.18 and 5.0224 ± 0.885 respectively. Among all patients, 95% were found to have metabolic abnormalities. The most common was hypercalciuria (54%) followed by hyperoxaluria in 28% patients. Hypocitraturia was seen in 21% patients. Distal renal tubular acidosis was found in 6% children. Only 5% children were having low magnesium level in their urine. Conclusion: Majority of the children with stone disease had underlying metabolic risk factor and in our setting, hypercalciuria is the most common one.Iram NazFarkhanda HafeezArmy Medical College Rawalpindiarticledistal renal tubular acidosishypercalciuriahypocitraturiametabolic workupMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1668-1671 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	distal renal tubular acidosis hypercalciuria hypocitraturia metabolic workup Medicine R Medicine (General) R5-920
spellingShingle	distal renal tubular acidosis hypercalciuria hypocitraturia metabolic workup Medicine R Medicine (General) R5-920 Iram Naz Farkhanda Hafeez METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME
description	Objectives: To evaluate the pediatric patients with renal calculi in terms of bio-metabolic profile. Study Design: Cross sectional study. Place and Duration of Study: Department of pediatric nephrology the Children’s Hospital and the Institute of Child Health Lahore over a period of 10 months from Nov 2016 to Sep 2017. Material and Methods: A total 85 patients with urolithiasis up to the age of 14 years were enrolled for study. Structured history and tailored investigations were collected from all the patients. Results of the physical examination, blood chemistry, and urinary excretion of metabolites (urinary calcium, citrate, magnesium and oxalate) were recorded. Results: Out of 85 patients; 65% were males and 35% were females (2:1); mean age at presentation was 8.15 ± 5.04 years. Hypertension was documented in 57% patients. Mean level of urea and creatinine was 73.02 ± 59mg/dl and 4.435 ± 4.024mg/dl respectively. Vitamin D level was 37 ± 15.6ng/ml while serum PTH level was 51.2941 ± 26.067pg/l. Serum calcium and phosphorus was 8.54 ± 1.18 and 5.0224 ± 0.885 respectively. Among all patients, 95% were found to have metabolic abnormalities. The most common was hypercalciuria (54%) followed by hyperoxaluria in 28% patients. Hypocitraturia was seen in 21% patients. Distal renal tubular acidosis was found in 6% children. Only 5% children were having low magnesium level in their urine. Conclusion: Majority of the children with stone disease had underlying metabolic risk factor and in our setting, hypercalciuria is the most common one.
format	article
author	Iram Naz Farkhanda Hafeez
author_facet	Iram Naz Farkhanda Hafeez
author_sort	Iram Naz
title	METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME
title_short	METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME
title_full	METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME
title_fullStr	METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME
title_full_unstemmed	METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME
title_sort	metabolic evaluation for pediatric renal stones - a stitch in time
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/961d17e6de3545de90b9809a86c53129
work_keys_str_mv	AT iramnaz metabolicevaluationforpediatricrenalstonesastitchintime AT farkhandahafeez metabolicevaluationforpediatricrenalstonesastitchintime
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METABOLIC EVALUATION FOR PEDIATRIC RENAL STONES - A STITCH IN TIME

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