INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING
Thirty-one isolates of M. tuberculosis was identified in Buryatia by MIRU-VNTR-24 typing and deletion analysis by RD105 and RD207. Beijing family strains accountedfor 67,4 % and had a variety of profiles with a prevalence (22,6 %) of two modern epidemic subtype Beijing MIT17 and MIT16. Strains Beiji...
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Scientific Сentre for Family Health and Human Reproduction Problems
2013
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oai:doaj.org-article:961f9b87e583455eb0020a7de95bc94c2021-11-23T06:14:26ZINVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING2541-94202587-9596https://doaj.org/article/961f9b87e583455eb0020a7de95bc94c2013-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1464https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Thirty-one isolates of M. tuberculosis was identified in Buryatia by MIRU-VNTR-24 typing and deletion analysis by RD105 and RD207. Beijing family strains accountedfor 67,4 % and had a variety of profiles with a prevalence (22,6 %) of two modern epidemic subtype Beijing MIT17 and MIT16. Strains Beijing MIT 642 differed in the number of repeats of the variable loci, it may reflect a longer circulation of these subtypes without shaping their properties of epidemic circulating strains in modern populations, or they had epidemic importance in the past. It is also apparent heterogeneity in the number of loci among strains according to group LAM, T, and X, which requires additional research. The aim of this work was to determine the current epidemiologically important genotypes of Mycobacterium tuberculosis, as well as the genotypes had an epidemic importance in the past as an example of the region with a high prevalence of tuberculosis - the Republic of Buryatia.A. A. LatsO. B. OgarkovS. N. ZhdanovaA. N. ZarbuevL. S. UntanovaM. V. BadleevaB. D. ZanaevaO. Ts. TsydypovaScientific Сentre for Family Health and Human Reproduction Problemsarticlemolecular epidemiology of tuberculosispandemic genotype m. tuberculosisreconstruction of the history epidemicphylogenyScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(2), Pp 144-147 (2013) |
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DOAJ |
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DOAJ |
language |
RU |
topic |
molecular epidemiology of tuberculosis pandemic genotype m. tuberculosis reconstruction of the history epidemic phylogeny Science Q |
spellingShingle |
molecular epidemiology of tuberculosis pandemic genotype m. tuberculosis reconstruction of the history epidemic phylogeny Science Q A. A. Lats O. B. Ogarkov S. N. Zhdanova A. N. Zarbuev L. S. Untanova M. V. Badleeva B. D. Zanaeva O. Ts. Tsydypova INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING |
description |
Thirty-one isolates of M. tuberculosis was identified in Buryatia by MIRU-VNTR-24 typing and deletion analysis by RD105 and RD207. Beijing family strains accountedfor 67,4 % and had a variety of profiles with a prevalence (22,6 %) of two modern epidemic subtype Beijing MIT17 and MIT16. Strains Beijing MIT 642 differed in the number of repeats of the variable loci, it may reflect a longer circulation of these subtypes without shaping their properties of epidemic circulating strains in modern populations, or they had epidemic importance in the past. It is also apparent heterogeneity in the number of loci among strains according to group LAM, T, and X, which requires additional research. The aim of this work was to determine the current epidemiologically important genotypes of Mycobacterium tuberculosis, as well as the genotypes had an epidemic importance in the past as an example of the region with a high prevalence of tuberculosis - the Republic of Buryatia. |
format |
article |
author |
A. A. Lats O. B. Ogarkov S. N. Zhdanova A. N. Zarbuev L. S. Untanova M. V. Badleeva B. D. Zanaeva O. Ts. Tsydypova |
author_facet |
A. A. Lats O. B. Ogarkov S. N. Zhdanova A. N. Zarbuev L. S. Untanova M. V. Badleeva B. D. Zanaeva O. Ts. Tsydypova |
author_sort |
A. A. Lats |
title |
INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING |
title_short |
INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING |
title_full |
INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING |
title_fullStr |
INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING |
title_full_unstemmed |
INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING |
title_sort |
investigation phylogenetic relationships major genotypes mycobacterium tuberculosis by miru-vntr-24 genotyping |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2013 |
url |
https://doaj.org/article/961f9b87e583455eb0020a7de95bc94c |
work_keys_str_mv |
AT aalats investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping AT obogarkov investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping AT snzhdanova investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping AT anzarbuev investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping AT lsuntanova investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping AT mvbadleeva investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping AT bdzanaeva investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping AT otstsydypova investigationphylogeneticrelationshipsmajorgenotypesmycobacteriumtuberculosisbymiruvntr24genotyping |
_version_ |
1718417208726519808 |