INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING

Thirty-one isolates of M. tuberculosis was identified in Buryatia by MIRU-VNTR-24 typing and deletion analysis by RD105 and RD207. Beijing family strains accountedfor 67,4 % and had a variety of profiles with a prevalence (22,6 %) of two modern epidemic subtype Beijing MIT17 and MIT16. Strains Beiji...

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Autores principales: A. A. Lats, O. B. Ogarkov, S. N. Zhdanova, A. N. Zarbuev, L. S. Untanova, M. V. Badleeva, B. D. Zanaeva, O. Ts. Tsydypova
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Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2013
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Acceso en línea:https://doaj.org/article/961f9b87e583455eb0020a7de95bc94c
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spelling oai:doaj.org-article:961f9b87e583455eb0020a7de95bc94c2021-11-23T06:14:26ZINVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING2541-94202587-9596https://doaj.org/article/961f9b87e583455eb0020a7de95bc94c2013-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1464https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Thirty-one isolates of M. tuberculosis was identified in Buryatia by MIRU-VNTR-24 typing and deletion analysis by RD105 and RD207. Beijing family strains accountedfor 67,4 % and had a variety of profiles with a prevalence (22,6 %) of two modern epidemic subtype Beijing MIT17 and MIT16. Strains Beijing MIT 642 differed in the number of repeats of the variable loci, it may reflect a longer circulation of these subtypes without shaping their properties of epidemic circulating strains in modern populations, or they had epidemic importance in the past. It is also apparent heterogeneity in the number of loci among strains according to group LAM, T, and X, which requires additional research. The aim of this work was to determine the current epidemiologically important genotypes of Mycobacterium tuberculosis, as well as the genotypes had an epidemic importance in the past as an example of the region with a high prevalence of tuberculosis - the Republic of Buryatia.A. A. LatsO. B. OgarkovS. N. ZhdanovaA. N. ZarbuevL. S. UntanovaM. V. BadleevaB. D. ZanaevaO. Ts. TsydypovaScientific Сentre for Family Health and Human Reproduction Problemsarticlemolecular epidemiology of tuberculosispandemic genotype m. tuberculosisreconstruction of the history epidemicphylogenyScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(2), Pp 144-147 (2013)
institution DOAJ
collection DOAJ
language RU
topic molecular epidemiology of tuberculosis
pandemic genotype m. tuberculosis
reconstruction of the history epidemic
phylogeny
Science
Q
spellingShingle molecular epidemiology of tuberculosis
pandemic genotype m. tuberculosis
reconstruction of the history epidemic
phylogeny
Science
Q
A. A. Lats
O. B. Ogarkov
S. N. Zhdanova
A. N. Zarbuev
L. S. Untanova
M. V. Badleeva
B. D. Zanaeva
O. Ts. Tsydypova
INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING
description Thirty-one isolates of M. tuberculosis was identified in Buryatia by MIRU-VNTR-24 typing and deletion analysis by RD105 and RD207. Beijing family strains accountedfor 67,4 % and had a variety of profiles with a prevalence (22,6 %) of two modern epidemic subtype Beijing MIT17 and MIT16. Strains Beijing MIT 642 differed in the number of repeats of the variable loci, it may reflect a longer circulation of these subtypes without shaping their properties of epidemic circulating strains in modern populations, or they had epidemic importance in the past. It is also apparent heterogeneity in the number of loci among strains according to group LAM, T, and X, which requires additional research. The aim of this work was to determine the current epidemiologically important genotypes of Mycobacterium tuberculosis, as well as the genotypes had an epidemic importance in the past as an example of the region with a high prevalence of tuberculosis - the Republic of Buryatia.
format article
author A. A. Lats
O. B. Ogarkov
S. N. Zhdanova
A. N. Zarbuev
L. S. Untanova
M. V. Badleeva
B. D. Zanaeva
O. Ts. Tsydypova
author_facet A. A. Lats
O. B. Ogarkov
S. N. Zhdanova
A. N. Zarbuev
L. S. Untanova
M. V. Badleeva
B. D. Zanaeva
O. Ts. Tsydypova
author_sort A. A. Lats
title INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING
title_short INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING
title_full INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING
title_fullStr INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING
title_full_unstemmed INVESTIGATION PHYLOGENETIC RELATIONSHIPS MAJOR GENOTYPES MYCOBACTERIUM TUBERCULOSIS BY MIRU-VNTR-24 GENOTYPING
title_sort investigation phylogenetic relationships major genotypes mycobacterium tuberculosis by miru-vntr-24 genotyping
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2013
url https://doaj.org/article/961f9b87e583455eb0020a7de95bc94c
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