Ultrasound diagnostics of the dialysis-related amyloidosis

Dialysis-related amyloidosis (DRA) is a serious complication arising in the context of long-term hemodialysis or continuous ambulatory peritoneal dialysis. DRA predominantly involves the osteoarticular system and is clinically manifested by erosive and destructive osteoarthropathies and carpal tunne...

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Main Author:	E. V. Polukhina
Format:	article
Language:	RU
Published:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Subjects:	ultrasound diagnostics chronic kidney disease dialysis amyloidarthropathy Science Q
Online Access:	https://doaj.org/article/962811b666714cde8451d497fb2d7796
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spelling	oai:doaj.org-article:962811b666714cde8451d497fb2d77962021-11-23T06:14:31ZUltrasound diagnostics of the dialysis-related amyloidosis2541-94202587-9596https://doaj.org/article/962811b666714cde8451d497fb2d77962015-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/7https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Dialysis-related amyloidosis (DRA) is a serious complication arising in the context of long-term hemodialysis or continuous ambulatory peritoneal dialysis. DRA predominantly involves the osteoarticular system and is clinically manifested by erosive and destructive osteoarthropathies and carpal tunnel syndrome. The aim of this study was to establish distinguishing features of the DRA in dialysis patients by using ultrasound. Joints and soft tissues of 200 patients with chronic kidney disease receiving dialysis were studied by ultrasound. Fourteen patients (7,0%) had clinically and radiologically evident, biopsy proven DRA. In this group of patients, all patients were receiving hemodialysisfor an average of 168 months. There was positive correlation found between dialysis duration and presence of DRA (Rs = 0,667; p < 0,001). The relationship between presence of DRA and discovered joints changes using ultrasound is analyzed. More frequent involvement in the pathological process shoulder (92,9%) and hip joints (64,3%) was noted. There were statistically significant differences in rotator cuff thickness and hip joint anterior synovial space thickness in patients with DRA compare to general group (p < 0,001). Ultrasound is a highly informative method of diagnosing DRA in patients with end-stage renal disease. It provides detailed soft tissue and joint description substituting other imaging modalities.E. V. PolukhinaScientific Сentre for Family Health and Human Reproduction Problemsarticleultrasound diagnosticschronic kidney diseasedialysisamyloidarthropathyScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 34-38 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	ultrasound diagnostics chronic kidney disease dialysis amyloidarthropathy Science Q
spellingShingle	ultrasound diagnostics chronic kidney disease dialysis amyloidarthropathy Science Q E. V. Polukhina Ultrasound diagnostics of the dialysis-related amyloidosis
description	Dialysis-related amyloidosis (DRA) is a serious complication arising in the context of long-term hemodialysis or continuous ambulatory peritoneal dialysis. DRA predominantly involves the osteoarticular system and is clinically manifested by erosive and destructive osteoarthropathies and carpal tunnel syndrome. The aim of this study was to establish distinguishing features of the DRA in dialysis patients by using ultrasound. Joints and soft tissues of 200 patients with chronic kidney disease receiving dialysis were studied by ultrasound. Fourteen patients (7,0%) had clinically and radiologically evident, biopsy proven DRA. In this group of patients, all patients were receiving hemodialysisfor an average of 168 months. There was positive correlation found between dialysis duration and presence of DRA (Rs = 0,667; p < 0,001). The relationship between presence of DRA and discovered joints changes using ultrasound is analyzed. More frequent involvement in the pathological process shoulder (92,9%) and hip joints (64,3%) was noted. There were statistically significant differences in rotator cuff thickness and hip joint anterior synovial space thickness in patients with DRA compare to general group (p < 0,001). Ultrasound is a highly informative method of diagnosing DRA in patients with end-stage renal disease. It provides detailed soft tissue and joint description substituting other imaging modalities.
format	article
author	E. V. Polukhina
author_facet	E. V. Polukhina
author_sort	E. V. Polukhina
title	Ultrasound diagnostics of the dialysis-related amyloidosis
title_short	Ultrasound diagnostics of the dialysis-related amyloidosis
title_full	Ultrasound diagnostics of the dialysis-related amyloidosis
title_fullStr	Ultrasound diagnostics of the dialysis-related amyloidosis
title_full_unstemmed	Ultrasound diagnostics of the dialysis-related amyloidosis
title_sort	ultrasound diagnostics of the dialysis-related amyloidosis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/962811b666714cde8451d497fb2d7796
work_keys_str_mv	AT evpolukhina ultrasounddiagnosticsofthedialysisrelatedamyloidosis
_version_	1718417084061319168

Ultrasound diagnostics of the dialysis-related amyloidosis

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