A large and intact viral particle penetrates the endoplasmic reticulum membrane to reach the cytosol.
Non-enveloped viruses penetrate host membranes to infect cells. A cell-based assay was used to probe the endoplasmic reticulum (ER)-to-cytosol membrane transport of the non-enveloped SV40. We found that, upon ER arrival, SV40 is released into the lumen and undergoes sequential disulfide bond disrupt...
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Auteurs principaux: | Takamasa Inoue, Billy Tsai |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/962b6071a809416c8cf2fe122e6a7d0a |
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