A large and intact viral particle penetrates the endoplasmic reticulum membrane to reach the cytosol.

Non-enveloped viruses penetrate host membranes to infect cells. A cell-based assay was used to probe the endoplasmic reticulum (ER)-to-cytosol membrane transport of the non-enveloped SV40. We found that, upon ER arrival, SV40 is released into the lumen and undergoes sequential disulfide bond disrupt...

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Auteurs principaux: Takamasa Inoue, Billy Tsai
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/962b6071a809416c8cf2fe122e6a7d0a
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