Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells

Living cells and tissues experience various complex modes of forces but how different force modes impact gene expression is elusive. Here authors apply forces via magnetic beads to integrins on a cell surface and observe force-mode dependent chromatin stretching and gene upregulation in cells and id...

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Bibliographic Details
Main Authors: Fuxiang Wei, Xiangyu Xu, Cunyu Zhang, Yawen Liao, Baohua Ji, Ning Wang
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/962d1725337f4e5b8e220adf785b2708
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