Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study

Background: Studies have suggested that repetitive transcranial magnetic stimulation (rTMS) could be efficacious in the treatment of major depression and other psychiatric indications. Alcohol-dependence syndrome is difficult to treat, and the relapse rate is high, even following the standard treatm...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Anindya Kumar Gupta, Amit Kumar, N Chandrashekhar
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	repetitive transcranial magnetic stimulation alcohol dependence syndrome adjunctive treatment Psychiatry RC435-571 Industrial psychology HF5548.7-5548.85
Acceso en línea:	https://doaj.org/article/962f77b19f284546aa199fc7dd18dd2b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:962f77b19f284546aa199fc7dd18dd2b
record_format	dspace
spelling	oai:doaj.org-article:962f77b19f284546aa199fc7dd18dd2b2021-11-12T10:11:30ZAdjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study0972-67480976-279510.4103/0972-6748.328795https://doaj.org/article/962f77b19f284546aa199fc7dd18dd2b2021-01-01T00:00:00Zhttp://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2021;volume=30;issue=3;spage=93;epage=96;aulast=Guptahttps://doaj.org/toc/0972-6748https://doaj.org/toc/0976-2795Background: Studies have suggested that repetitive transcranial magnetic stimulation (rTMS) could be efficacious in the treatment of major depression and other psychiatric indications. Alcohol-dependence syndrome is difficult to treat, and the relapse rate is high, even following the standard treatment protocol. No study has been done so far in India for the use of rTMS as an adjuvant therapy in the relapse prevention of patients with alcohol-dependence syndrome. Hence, the current study is an open-label study to explore the same. Aim: The aim of this study was to study the feasibility of rTMS in alcohol-dependence syndrome patients, the side effects if any, and the number of relapses that they may suffer from vis-a-vis patients with standard treatment protocols. Materials and Methods: In a prospective, open-label study design, 100 freshly diagnosed cases of alcohol-dependence syndrome were included, and after suitable randomization, half of them were given adjuvant rTMS along with standard treatment and the rest received only standard treatment. The rates of relapse into drinking were compared for both groups. The data were compiled and analyzed with appropriate statistical methods. Results: Participants given adjuvant rTMS showed significantly less number of relapses into drinking compared to the control group on standard treatment for alcohol-dependence syndrome. Conclusion: In the present study, though the sample size is small, a significant change with this novel treatment has been found. Whether this change is maintained over a period of time is to be seen by other longitudinal studies.Anindya Kumar GuptaAmit KumarN ChandrashekharWolters Kluwer Medknow Publicationsarticlerepetitive transcranial magnetic stimulationalcohol dependence syndromeadjunctive treatmentPsychiatryRC435-571Industrial psychologyHF5548.7-5548.85ENIndustrial Psychiatry Journal, Vol 30, Iss 3, Pp 93-96 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	repetitive transcranial magnetic stimulation alcohol dependence syndrome adjunctive treatment Psychiatry RC435-571 Industrial psychology HF5548.7-5548.85
spellingShingle	repetitive transcranial magnetic stimulation alcohol dependence syndrome adjunctive treatment Psychiatry RC435-571 Industrial psychology HF5548.7-5548.85 Anindya Kumar Gupta Amit Kumar N Chandrashekhar Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study
description	Background: Studies have suggested that repetitive transcranial magnetic stimulation (rTMS) could be efficacious in the treatment of major depression and other psychiatric indications. Alcohol-dependence syndrome is difficult to treat, and the relapse rate is high, even following the standard treatment protocol. No study has been done so far in India for the use of rTMS as an adjuvant therapy in the relapse prevention of patients with alcohol-dependence syndrome. Hence, the current study is an open-label study to explore the same. Aim: The aim of this study was to study the feasibility of rTMS in alcohol-dependence syndrome patients, the side effects if any, and the number of relapses that they may suffer from vis-a-vis patients with standard treatment protocols. Materials and Methods: In a prospective, open-label study design, 100 freshly diagnosed cases of alcohol-dependence syndrome were included, and after suitable randomization, half of them were given adjuvant rTMS along with standard treatment and the rest received only standard treatment. The rates of relapse into drinking were compared for both groups. The data were compiled and analyzed with appropriate statistical methods. Results: Participants given adjuvant rTMS showed significantly less number of relapses into drinking compared to the control group on standard treatment for alcohol-dependence syndrome. Conclusion: In the present study, though the sample size is small, a significant change with this novel treatment has been found. Whether this change is maintained over a period of time is to be seen by other longitudinal studies.
format	article
author	Anindya Kumar Gupta Amit Kumar N Chandrashekhar
author_facet	Anindya Kumar Gupta Amit Kumar N Chandrashekhar
author_sort	Anindya Kumar Gupta
title	Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study
title_short	Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study
title_full	Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study
title_fullStr	Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study
title_full_unstemmed	Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study
title_sort	adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: an outcome study
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/962f77b19f284546aa199fc7dd18dd2b
work_keys_str_mv	AT anindyakumargupta adjuvanttreatmentwithrepetitivetranscranialmagneticstimulationinfreshlydiagnosedalcoholdependencesyndromepatientsfromanindustryanoutcomestudy AT amitkumar adjuvanttreatmentwithrepetitivetranscranialmagneticstimulationinfreshlydiagnosedalcoholdependencesyndromepatientsfromanindustryanoutcomestudy AT nchandrashekhar adjuvanttreatmentwithrepetitivetranscranialmagneticstimulationinfreshlydiagnosedalcoholdependencesyndromepatientsfromanindustryanoutcomestudy
_version_	1718431004411035648

Adjuvant treatment with repetitive transcranial magnetic stimulation in freshly diagnosed alcohol-dependence syndrome patients from an industry: An outcome study

Ejemplares similares