Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention

Abstract This study compared changes in plasma complement component 1q (C1q), apelin and adropin concentrations in older obese women after descending (DSW) and ascending stair walking (ASW) training (n = 15/group) performed twice a week for 12 weeks, with gradual increases in exercise time from 5 to...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Trevor C. Chen, Tsang-Hai Huang, Wei-Chin Tseng, Kuo-Wei Tseng, Chung-Chan Hsieh, Mei-Yen Chen, Tai-Ying Chou, Yuh-Chuan Huang, Hsin-Lian Chen, Kazunori Nosaka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/96483ce2c7fc47a99ee4f0eb7c246735
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:96483ce2c7fc47a99ee4f0eb7c246735
record_format	dspace
spelling	oai:doaj.org-article:96483ce2c7fc47a99ee4f0eb7c2467352021-12-02T15:25:34ZChanges in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention10.1038/s41598-021-96631-x2045-2322https://doaj.org/article/96483ce2c7fc47a99ee4f0eb7c2467352021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96631-xhttps://doaj.org/toc/2045-2322Abstract This study compared changes in plasma complement component 1q (C1q), apelin and adropin concentrations in older obese women after descending (DSW) and ascending stair walking (ASW) training (n = 15/group) performed twice a week for 12 weeks, with gradual increases in exercise time from 5 to 60 min. Fasting blood samples were collected 3 days before the first and 4 days after the last training session. The improvements in the maximal voluntary isometric contraction (MVIC) strength of the knee extensors, functional physical fitness [e.g., 30-s chair stand (CS) performance], resting systolic blood pressure (SBP), insulin sensitivity [e.g., oral glucose tolerance test (OGTT)] and blood lipid profiles [e.g., total cholesterol (TC)] were greater (p < 0.05) in the DSW than ASW group. Plasma C1q decreased (− 51 ± 30%), and apelin (23 ± 15%) and adropin (127 ± 106%) increased (p ≤ .0.05) only after DSW. Significant (p ≤ 0.01) partial correlations were found between the pre- to post-DSW changes in C1q, apelin or adropin and changes in outcome measures [e.g., C1q and MVIC (r = − 0.837), apelin and SBP (r = − 0.854), and andropin and OGTT (r = − 0.729)]. These results showed that greater decreases in plasma C1q and greater increases in apelin and adropin concentrations were associated with greater improvements in outcome measures after DSW than after ASW.Trevor C. ChenTsang-Hai HuangWei-Chin TsengKuo-Wei TsengChung-Chan HsiehMei-Yen ChenTai-Ying ChouYuh-Chuan HuangHsin-Lian ChenKazunori NosakaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Trevor C. Chen Tsang-Hai Huang Wei-Chin Tseng Kuo-Wei Tseng Chung-Chan Hsieh Mei-Yen Chen Tai-Ying Chou Yuh-Chuan Huang Hsin-Lian Chen Kazunori Nosaka Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
description	Abstract This study compared changes in plasma complement component 1q (C1q), apelin and adropin concentrations in older obese women after descending (DSW) and ascending stair walking (ASW) training (n = 15/group) performed twice a week for 12 weeks, with gradual increases in exercise time from 5 to 60 min. Fasting blood samples were collected 3 days before the first and 4 days after the last training session. The improvements in the maximal voluntary isometric contraction (MVIC) strength of the knee extensors, functional physical fitness [e.g., 30-s chair stand (CS) performance], resting systolic blood pressure (SBP), insulin sensitivity [e.g., oral glucose tolerance test (OGTT)] and blood lipid profiles [e.g., total cholesterol (TC)] were greater (p < 0.05) in the DSW than ASW group. Plasma C1q decreased (− 51 ± 30%), and apelin (23 ± 15%) and adropin (127 ± 106%) increased (p ≤ .0.05) only after DSW. Significant (p ≤ 0.01) partial correlations were found between the pre- to post-DSW changes in C1q, apelin or adropin and changes in outcome measures [e.g., C1q and MVIC (r = − 0.837), apelin and SBP (r = − 0.854), and andropin and OGTT (r = − 0.729)]. These results showed that greater decreases in plasma C1q and greater increases in apelin and adropin concentrations were associated with greater improvements in outcome measures after DSW than after ASW.
format	article
author	Trevor C. Chen Tsang-Hai Huang Wei-Chin Tseng Kuo-Wei Tseng Chung-Chan Hsieh Mei-Yen Chen Tai-Ying Chou Yuh-Chuan Huang Hsin-Lian Chen Kazunori Nosaka
author_facet	Trevor C. Chen Tsang-Hai Huang Wei-Chin Tseng Kuo-Wei Tseng Chung-Chan Hsieh Mei-Yen Chen Tai-Ying Chou Yuh-Chuan Huang Hsin-Lian Chen Kazunori Nosaka
author_sort	Trevor C. Chen
title	Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
title_short	Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
title_full	Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
title_fullStr	Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
title_full_unstemmed	Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
title_sort	changes in plasma c1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/96483ce2c7fc47a99ee4f0eb7c246735
work_keys_str_mv	AT trevorcchen changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT tsanghaihuang changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT weichintseng changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT kuoweitseng changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT chungchanhsieh changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT meiyenchen changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT taiyingchou changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT yuhchuanhuang changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT hsinlianchen changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention AT kazunorinosaka changesinplasmac1qapelinandadropinconcentrationsinolderadultsafterdescendingandascendingstairwalkingintervention
_version_	1718387278754086912

Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention

Ejemplares similares