Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection

Heather M Fitzgerald,1 Jason Shepherd,2 Hollie Bailey,2 Mia Berry,2 Jack Wright,2 Maxine Chen3 1Lundbeck LLC, Deerfield, IL, USA; 2Adelphi Real World, Bollington, UK; 3Otsuka Pharmaceutical & Commercial Development, Inc., Princeton, NJ, USACorrespondence: Maxine ChenOtsuka Pharmaceutical & C...

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Autores principales:	Fitzgerald HM, Shepherd J, Bailey H, Berry M, Wright J, Chen M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	long-acting injectable antipsychotic oral antipsychotic real-world survey schizophrenia treatment goals treatment preferences Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/964c22818f9941159df09b9df3e97282
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spelling	oai:doaj.org-article:964c22818f9941159df09b9df3e972822021-12-02T19:36:07ZTreatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection1178-2021https://doaj.org/article/964c22818f9941159df09b9df3e972822021-10-01T00:00:00Zhttps://www.dovepress.com/treatment-goals-in-schizophrenia-a-real-world-survey-of-patients-psych-peer-reviewed-fulltext-article-NDThttps://doaj.org/toc/1178-2021Heather M Fitzgerald,1 Jason Shepherd,2 Hollie Bailey,2 Mia Berry,2 Jack Wright,2 Maxine Chen3 1Lundbeck LLC, Deerfield, IL, USA; 2Adelphi Real World, Bollington, UK; 3Otsuka Pharmaceutical & Commercial Development, Inc., Princeton, NJ, USACorrespondence: Maxine ChenOtsuka Pharmaceutical & Commercial Development, Inc., 508 Carnegie Center, Princeton, NJ, 08540, USATel +1 609-524-6788Email Maxine.Chen@Otsuka-US.comPurpose: To understand similarities and differences in patient treatment goals as selected by US psychiatrists, adult patients with schizophrenia, and their caregivers in a real-world setting in the United States, including stratification by current medication and age.Patients and Methods: Data were drawn from the Adelphi Schizophrenia Disease Specific Programme™, a point-in-time survey of psychiatrists and their consulting adult patients with schizophrenia, conducted from June to October 2019. Psychiatrists completed record forms for their next 8 consecutive outpatients and (where possible) 2 inpatients matching inclusion criteria. Participating psychiatrists, patients, and caregivers completed treatment goal questionnaires as part of the survey.Results: Psychiatrists (n = 124) provided data on 1204 patients with schizophrenia, including 1135 on drug treatment (207 inpatients [18%] and 928 outpatients [82%]); questionnaires were completed by 555 patients and 135 caregivers. Decrease in disease symptoms was identified as the most important patient treatment goal by patients (64%), psychiatrists (selecting for 63% of patients), and caregivers (selecting for 68% of patients). Patients, psychiatrists, and caregivers similarly rated the least important goals (less sexual problems and less weight gain). Patients indicated their current medication helped to reach their most important goals: decrease in disease symptoms (68%) and thinking more clearly (39%). Findings based on analysis of treatment goals by treatment and age were similar to overall trends.Conclusion: These findings, including identification of a primary consensus goal of decrease in disease symptoms, may help with discussions between patients with schizophrenia, psychiatrists, and caregivers to inform effective management strategies and encourage shared decision-making.Keywords: long-acting injectable antipsychotic, oral antipsychotic, real-world survey, schizophrenia, treatment goals, treatment preferencesFitzgerald HMShepherd JBailey HBerry MWright JChen MDove Medical Pressarticlelong-acting injectable antipsychoticoral antipsychoticreal-world surveyschizophreniatreatment goalstreatment preferencesNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 17, Pp 3215-3228 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	long-acting injectable antipsychotic oral antipsychotic real-world survey schizophrenia treatment goals treatment preferences Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	long-acting injectable antipsychotic oral antipsychotic real-world survey schizophrenia treatment goals treatment preferences Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Fitzgerald HM Shepherd J Bailey H Berry M Wright J Chen M Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection
description	Heather M Fitzgerald,1 Jason Shepherd,2 Hollie Bailey,2 Mia Berry,2 Jack Wright,2 Maxine Chen3 1Lundbeck LLC, Deerfield, IL, USA; 2Adelphi Real World, Bollington, UK; 3Otsuka Pharmaceutical & Commercial Development, Inc., Princeton, NJ, USACorrespondence: Maxine ChenOtsuka Pharmaceutical & Commercial Development, Inc., 508 Carnegie Center, Princeton, NJ, 08540, USATel +1 609-524-6788Email Maxine.Chen@Otsuka-US.comPurpose: To understand similarities and differences in patient treatment goals as selected by US psychiatrists, adult patients with schizophrenia, and their caregivers in a real-world setting in the United States, including stratification by current medication and age.Patients and Methods: Data were drawn from the Adelphi Schizophrenia Disease Specific Programme™, a point-in-time survey of psychiatrists and their consulting adult patients with schizophrenia, conducted from June to October 2019. Psychiatrists completed record forms for their next 8 consecutive outpatients and (where possible) 2 inpatients matching inclusion criteria. Participating psychiatrists, patients, and caregivers completed treatment goal questionnaires as part of the survey.Results: Psychiatrists (n = 124) provided data on 1204 patients with schizophrenia, including 1135 on drug treatment (207 inpatients [18%] and 928 outpatients [82%]); questionnaires were completed by 555 patients and 135 caregivers. Decrease in disease symptoms was identified as the most important patient treatment goal by patients (64%), psychiatrists (selecting for 63% of patients), and caregivers (selecting for 68% of patients). Patients, psychiatrists, and caregivers similarly rated the least important goals (less sexual problems and less weight gain). Patients indicated their current medication helped to reach their most important goals: decrease in disease symptoms (68%) and thinking more clearly (39%). Findings based on analysis of treatment goals by treatment and age were similar to overall trends.Conclusion: These findings, including identification of a primary consensus goal of decrease in disease symptoms, may help with discussions between patients with schizophrenia, psychiatrists, and caregivers to inform effective management strategies and encourage shared decision-making.Keywords: long-acting injectable antipsychotic, oral antipsychotic, real-world survey, schizophrenia, treatment goals, treatment preferences
format	article
author	Fitzgerald HM Shepherd J Bailey H Berry M Wright J Chen M
author_facet	Fitzgerald HM Shepherd J Bailey H Berry M Wright J Chen M
author_sort	Fitzgerald HM
title	Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection
title_short	Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection
title_full	Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection
title_fullStr	Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection
title_full_unstemmed	Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection
title_sort	treatment goals in schizophrenia: a real-world survey of patients, psychiatrists, and caregivers in the united states, with an analysis of current treatment (long-acting injectable vs oral antipsychotics) and goal selection
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/964c22818f9941159df09b9df3e97282
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Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection

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