Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy

Heterologous immunity can confer protection between related viruses. Here the authors show that prior exposure to Dengue virus can protect against subsequent infection with Zika virus in the context of pregnancy, and crucially can prevent demise of the fetus in murine models of infection.

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Autores principales:	Jose Angel Regla-Nava, Annie Elong Ngono, Karla M. Viramontes, Anh-Thy Huynh, Ying-Ting Wang, Anh-Viet T. Nguyen, Rebecca Salgado, Anila Mamidi, Kenneth Kim, Michael S. Diamond, Sujan Shresta
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/965298bef2f549858fe3ead0468da783
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spelling	oai:doaj.org-article:965298bef2f549858fe3ead0468da7832021-12-02T13:24:06ZCross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy10.1038/s41467-018-05458-02041-1723https://doaj.org/article/965298bef2f549858fe3ead0468da7832018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05458-0https://doaj.org/toc/2041-1723Heterologous immunity can confer protection between related viruses. Here the authors show that prior exposure to Dengue virus can protect against subsequent infection with Zika virus in the context of pregnancy, and crucially can prevent demise of the fetus in murine models of infection.Jose Angel Regla-NavaAnnie Elong NgonoKarla M. ViramontesAnh-Thy HuynhYing-Ting WangAnh-Viet T. NguyenRebecca SalgadoAnila MamidiKenneth KimMichael S. DiamondSujan ShrestaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jose Angel Regla-Nava Annie Elong Ngono Karla M. Viramontes Anh-Thy Huynh Ying-Ting Wang Anh-Viet T. Nguyen Rebecca Salgado Anila Mamidi Kenneth Kim Michael S. Diamond Sujan Shresta Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
description	Heterologous immunity can confer protection between related viruses. Here the authors show that prior exposure to Dengue virus can protect against subsequent infection with Zika virus in the context of pregnancy, and crucially can prevent demise of the fetus in murine models of infection.
format	article
author	Jose Angel Regla-Nava Annie Elong Ngono Karla M. Viramontes Anh-Thy Huynh Ying-Ting Wang Anh-Viet T. Nguyen Rebecca Salgado Anila Mamidi Kenneth Kim Michael S. Diamond Sujan Shresta
author_facet	Jose Angel Regla-Nava Annie Elong Ngono Karla M. Viramontes Anh-Thy Huynh Ying-Ting Wang Anh-Viet T. Nguyen Rebecca Salgado Anila Mamidi Kenneth Kim Michael S. Diamond Sujan Shresta
author_sort	Jose Angel Regla-Nava
title	Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
title_short	Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
title_full	Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
title_fullStr	Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
title_full_unstemmed	Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
title_sort	cross-reactive dengue virus-specific cd8+ t cells protect against zika virus during pregnancy
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/965298bef2f549858fe3ead0468da783
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Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy

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