Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.

<h4>Background</h4>Why are some people happier than others? This question has intrigued many researchers. However, limited work has addressed this question within a neuroscientific framework.<h4>Methods</h4>The present study investigated the neural correlates of trait happine...

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Autores principales:	Yangmei Luo, Xiting Huang, Zhen Yang, Baolin Li, Jie Liu, Dongtao Wei
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9665e5b88ef84fc096ca7cb09966dff2
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spelling	oai:doaj.org-article:9665e5b88ef84fc096ca7cb09966dff22021-11-18T08:37:43ZRegional homogeneity of intrinsic brain activity in happy and unhappy individuals.1932-620310.1371/journal.pone.0085181https://doaj.org/article/9665e5b88ef84fc096ca7cb09966dff22014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24454814/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Why are some people happier than others? This question has intrigued many researchers. However, limited work has addressed this question within a neuroscientific framework.<h4>Methods</h4>The present study investigated the neural correlates of trait happiness using the resting-state functional magnetic resonance imaging (rs-fMRI) approach. Specifically, regional homogeneity (ReHo) was examined on two groups of young adults: happy and unhappy individuals (N = 25 per group).<h4>Results</h4>Decreased ReHo in unhappy relative to happy individuals was observed within prefrontal cortex, medial temporal lobe, superior temporal lobe, and retrosplenial cortex. In contrast, increased ReHo in unhappy relative to happy individuals was observed within the dorsolateral prefrontal cortex, middle cingulate gyrus, putamen, and thalamus. In addition, the ReHo within the left thalamus was negatively correlated with Chinese Happiness Inventory (CHI) score within the happy group.<h4>Limitations</h4>As an exploratory study, we examined how general trait happiness is reflected in the regional homogeneity of intrinsic brain activity in a relatively small sample. Examining other types of happiness in a larger sample using a multitude of intrinsic brain activity indices are warranted for future work.<h4>Conclusions</h4>The local synchronization of BOLD signal is altered in unhappy individuals. The regions implicated in this alteration partly overlapped with previously identified default mode network, emotional circuitry, and rewarding system, suggesting that these systems may be involved in happiness.Yangmei LuoXiting HuangZhen YangBaolin LiJie LiuDongtao WeiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 1, p e85181 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yangmei Luo Xiting Huang Zhen Yang Baolin Li Jie Liu Dongtao Wei Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.
description	<h4>Background</h4>Why are some people happier than others? This question has intrigued many researchers. However, limited work has addressed this question within a neuroscientific framework.<h4>Methods</h4>The present study investigated the neural correlates of trait happiness using the resting-state functional magnetic resonance imaging (rs-fMRI) approach. Specifically, regional homogeneity (ReHo) was examined on two groups of young adults: happy and unhappy individuals (N = 25 per group).<h4>Results</h4>Decreased ReHo in unhappy relative to happy individuals was observed within prefrontal cortex, medial temporal lobe, superior temporal lobe, and retrosplenial cortex. In contrast, increased ReHo in unhappy relative to happy individuals was observed within the dorsolateral prefrontal cortex, middle cingulate gyrus, putamen, and thalamus. In addition, the ReHo within the left thalamus was negatively correlated with Chinese Happiness Inventory (CHI) score within the happy group.<h4>Limitations</h4>As an exploratory study, we examined how general trait happiness is reflected in the regional homogeneity of intrinsic brain activity in a relatively small sample. Examining other types of happiness in a larger sample using a multitude of intrinsic brain activity indices are warranted for future work.<h4>Conclusions</h4>The local synchronization of BOLD signal is altered in unhappy individuals. The regions implicated in this alteration partly overlapped with previously identified default mode network, emotional circuitry, and rewarding system, suggesting that these systems may be involved in happiness.
format	article
author	Yangmei Luo Xiting Huang Zhen Yang Baolin Li Jie Liu Dongtao Wei
author_facet	Yangmei Luo Xiting Huang Zhen Yang Baolin Li Jie Liu Dongtao Wei
author_sort	Yangmei Luo
title	Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.
title_short	Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.
title_full	Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.
title_fullStr	Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.
title_full_unstemmed	Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.
title_sort	regional homogeneity of intrinsic brain activity in happy and unhappy individuals.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/9665e5b88ef84fc096ca7cb09966dff2
work_keys_str_mv	AT yangmeiluo regionalhomogeneityofintrinsicbrainactivityinhappyandunhappyindividuals AT xitinghuang regionalhomogeneityofintrinsicbrainactivityinhappyandunhappyindividuals AT zhenyang regionalhomogeneityofintrinsicbrainactivityinhappyandunhappyindividuals AT baolinli regionalhomogeneityofintrinsicbrainactivityinhappyandunhappyindividuals AT jieliu regionalhomogeneityofintrinsicbrainactivityinhappyandunhappyindividuals AT dongtaowei regionalhomogeneityofintrinsicbrainactivityinhappyandunhappyindividuals
_version_	1718421575390199808

Regional homogeneity of intrinsic brain activity in happy and unhappy individuals.

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