Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life

Food allergy is triggered by IgE, but some individuals are not allergic to peanuts despite making peanut-specific IgE, and are considered peanut-tolerant. Here, the authors identify differences in blood immune cell composition of peanut-allergic and tolerant infants using mass cytometry, which may h...

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Autores principales:	Melanie R. Neeland, Sandra Andorf, Monali Manohar, Diane Dunham, Shu-Chen Lyu, Thanh D. Dang, Rachel L. Peters, Kirsten P. Perrett, Mimi L. K. Tang, Richard Saffery, Jennifer J. Koplin, Kari C. Nadeau
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/966c4c38a8dd4e93886f0419ac4fec6a
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spelling	oai:doaj.org-article:966c4c38a8dd4e93886f0419ac4fec6a2021-12-02T16:49:15ZMass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life10.1038/s41467-020-14919-42041-1723https://doaj.org/article/966c4c38a8dd4e93886f0419ac4fec6a2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14919-4https://doaj.org/toc/2041-1723Food allergy is triggered by IgE, but some individuals are not allergic to peanuts despite making peanut-specific IgE, and are considered peanut-tolerant. Here, the authors identify differences in blood immune cell composition of peanut-allergic and tolerant infants using mass cytometry, which may help uncover the mechanism of allergic tolerance.Melanie R. NeelandSandra AndorfMonali ManoharDiane DunhamShu-Chen LyuThanh D. DangRachel L. PetersKirsten P. PerrettMimi L. K. TangRichard SafferyJennifer J. KoplinKari C. NadeauNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Melanie R. Neeland Sandra Andorf Monali Manohar Diane Dunham Shu-Chen Lyu Thanh D. Dang Rachel L. Peters Kirsten P. Perrett Mimi L. K. Tang Richard Saffery Jennifer J. Koplin Kari C. Nadeau Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
description	Food allergy is triggered by IgE, but some individuals are not allergic to peanuts despite making peanut-specific IgE, and are considered peanut-tolerant. Here, the authors identify differences in blood immune cell composition of peanut-allergic and tolerant infants using mass cytometry, which may help uncover the mechanism of allergic tolerance.
format	article
author	Melanie R. Neeland Sandra Andorf Monali Manohar Diane Dunham Shu-Chen Lyu Thanh D. Dang Rachel L. Peters Kirsten P. Perrett Mimi L. K. Tang Richard Saffery Jennifer J. Koplin Kari C. Nadeau
author_facet	Melanie R. Neeland Sandra Andorf Monali Manohar Diane Dunham Shu-Chen Lyu Thanh D. Dang Rachel L. Peters Kirsten P. Perrett Mimi L. K. Tang Richard Saffery Jennifer J. Koplin Kari C. Nadeau
author_sort	Melanie R. Neeland
title	Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
title_short	Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
title_full	Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
title_fullStr	Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
title_full_unstemmed	Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
title_sort	mass cytometry reveals cellular fingerprint associated with ige+ peanut tolerance and allergy in early life
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/966c4c38a8dd4e93886f0419ac4fec6a
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Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life

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