Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems

Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis.

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Detalles Bibliográficos
Autores principales: Ashot Papikian, Wanlu Liu, Javier Gallego-Bartolomé, Steven E. Jacobsen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
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Acceso en línea:https://doaj.org/article/966d08acb09448ee9fe2347f8253f363
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Descripción
Sumario:Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis.