Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems
Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis.
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Nature Portfolio
2019
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oai:doaj.org-article:966d08acb09448ee9fe2347f8253f3632021-12-02T17:02:03ZSite-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems10.1038/s41467-019-08736-72041-1723https://doaj.org/article/966d08acb09448ee9fe2347f8253f3632019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08736-7https://doaj.org/toc/2041-1723Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis.Ashot PapikianWanlu LiuJavier Gallego-BartoloméSteven E. JacobsenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Ashot Papikian Wanlu Liu Javier Gallego-Bartolomé Steven E. Jacobsen Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems |
description |
Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis. |
format |
article |
author |
Ashot Papikian Wanlu Liu Javier Gallego-Bartolomé Steven E. Jacobsen |
author_facet |
Ashot Papikian Wanlu Liu Javier Gallego-Bartolomé Steven E. Jacobsen |
author_sort |
Ashot Papikian |
title |
Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems |
title_short |
Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems |
title_full |
Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems |
title_fullStr |
Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems |
title_full_unstemmed |
Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems |
title_sort |
site-specific manipulation of arabidopsis loci using crispr-cas9 suntag systems |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/966d08acb09448ee9fe2347f8253f363 |
work_keys_str_mv |
AT ashotpapikian sitespecificmanipulationofarabidopsislociusingcrisprcas9suntagsystems AT wanluliu sitespecificmanipulationofarabidopsislociusingcrisprcas9suntagsystems AT javiergallegobartolome sitespecificmanipulationofarabidopsislociusingcrisprcas9suntagsystems AT stevenejacobsen sitespecificmanipulationofarabidopsislociusingcrisprcas9suntagsystems |
_version_ |
1718381983570067456 |