Pharmacogenetic markers of chemotherapy toxicity in gastrointestinal tumors: a preliminary analysis

Aim. To assess the association between the carriage of minor allelic variants of 8 genes that encode key enzymes involved in the metabolism of anticancer drugs (DPYD, GSTP1, MTHFR, UGT1A1) and cell repair (XPC, ERCC1, TYMP, NQO1) and the severity of adverse drug events in patients with common gastro...

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Main Authors: Denis S. Fedorinov, Rustam N. Geidarov, Igor A. Shashkov, Vladimir M. Mikhailovich, Marina A. Lyadova, Ilya A. Pokataev, Vladimir K. Lyadov
Format: article
Language:RU
Published: IP Habib O.N. 2021
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Online Access:https://doaj.org/article/967f135a4f9d43188148f60682a5b165
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