FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
Various parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the p...
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2014
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oai:doaj.org-article:96842aa55a1a4833b22a383785b669e12021-11-18T08:03:38ZFUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION1563-06252313-741X10.15789/1563-0625-2013-2-169-176https://doaj.org/article/96842aa55a1a4833b22a383785b669e12014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/129https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XVarious parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the patients, regardless of the disease stage, NВT scores were higher, and NET values were lower, than in control group. In stimulated cultures, NВT response was decreased, whereas NET parameters were higher than reference values. The changes in NET, but not NВT scores, were more pronounced in patients during the disease exacerbtion and in combined form of herpesvirus infection.N. V. GusakovaI. A. NovikovaSPb RAACIarticleherpes infectionfunctional activity of neutrophilsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 2, Pp 169-176 (2014) |
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DOAJ |
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topic |
herpes infection functional activity of neutrophils Immunologic diseases. Allergy RC581-607 |
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herpes infection functional activity of neutrophils Immunologic diseases. Allergy RC581-607 N. V. Gusakova I. A. Novikova FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
description |
Various parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the patients, regardless of the disease stage, NВT scores were higher, and NET values were lower, than in control group. In stimulated cultures, NВT response was decreased, whereas NET parameters were higher than reference values. The changes in NET, but not NВT scores, were more pronounced in patients during the disease exacerbtion and in combined form of herpesvirus infection. |
format |
article |
author |
N. V. Gusakova I. A. Novikova |
author_facet |
N. V. Gusakova I. A. Novikova |
author_sort |
N. V. Gusakova |
title |
FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
title_short |
FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
title_full |
FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
title_fullStr |
FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
title_full_unstemmed |
FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
title_sort |
functional activities of neutrophils in chronic recurrent herpetic infection |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/96842aa55a1a4833b22a383785b669e1 |
work_keys_str_mv |
AT nvgusakova functionalactivitiesofneutrophilsinchronicrecurrentherpeticinfection AT ianovikova functionalactivitiesofneutrophilsinchronicrecurrentherpeticinfection |
_version_ |
1718422559136940032 |