FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION

Various parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the p...

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Autores principales: N. V. Gusakova, I. A. Novikova
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/96842aa55a1a4833b22a383785b669e1
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spelling oai:doaj.org-article:96842aa55a1a4833b22a383785b669e12021-11-18T08:03:38ZFUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION1563-06252313-741X10.15789/1563-0625-2013-2-169-176https://doaj.org/article/96842aa55a1a4833b22a383785b669e12014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/129https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XVarious parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the patients, regardless of the disease stage, NВT scores were higher, and NET values were lower, than in control group. In stimulated cultures, NВT response was decreased, whereas NET parameters were higher than reference values. The changes in NET, but not NВT scores, were more pronounced in patients during the disease exacerbtion and in combined form of herpesvirus infection.N. V. GusakovaI. A. NovikovaSPb RAACIarticleherpes infectionfunctional activity of neutrophilsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 2, Pp 169-176 (2014)
institution DOAJ
collection DOAJ
language RU
topic herpes infection
functional activity of neutrophils
Immunologic diseases. Allergy
RC581-607
spellingShingle herpes infection
functional activity of neutrophils
Immunologic diseases. Allergy
RC581-607
N. V. Gusakova
I. A. Novikova
FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
description Various parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the patients, regardless of the disease stage, NВT scores were higher, and NET values were lower, than in control group. In stimulated cultures, NВT response was decreased, whereas NET parameters were higher than reference values. The changes in NET, but not NВT scores, were more pronounced in patients during the disease exacerbtion and in combined form of herpesvirus infection.
format article
author N. V. Gusakova
I. A. Novikova
author_facet N. V. Gusakova
I. A. Novikova
author_sort N. V. Gusakova
title FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
title_short FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
title_full FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
title_fullStr FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
title_full_unstemmed FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
title_sort functional activities of neutrophils in chronic recurrent herpetic infection
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/96842aa55a1a4833b22a383785b669e1
work_keys_str_mv AT nvgusakova functionalactivitiesofneutrophilsinchronicrecurrentherpeticinfection
AT ianovikova functionalactivitiesofneutrophilsinchronicrecurrentherpeticinfection
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