Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity

Angiogenesis is essential for solid tumor progression. Here, the authors interrogate the proteome of pancreatic cancer endothelium via phage display and identify hornerin as a critical protein whose expression is essential to maintain the pancreatic cancer vasculature through a VEGF-independent mech...

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Autores principales:	Michael F. Gutknecht, Marc E. Seaman, Bo Ning, Daniel Auger Cornejo, Emily Mugler, Patrick F. Antkowiak, Christopher A. Moskaluk, Song Hu, Frederick H. Epstein, Kimberly A. Kelly
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/968ae9dba40541f79ec82b4f597514db
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spelling	oai:doaj.org-article:968ae9dba40541f79ec82b4f597514db2021-12-02T15:38:51ZIdentification of the S100 fused-type protein hornerin as a regulator of tumor vascularity10.1038/s41467-017-00488-62041-1723https://doaj.org/article/968ae9dba40541f79ec82b4f597514db2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00488-6https://doaj.org/toc/2041-1723Angiogenesis is essential for solid tumor progression. Here, the authors interrogate the proteome of pancreatic cancer endothelium via phage display and identify hornerin as a critical protein whose expression is essential to maintain the pancreatic cancer vasculature through a VEGF-independent mechanism.Michael F. GutknechtMarc E. SeamanBo NingDaniel Auger CornejoEmily MuglerPatrick F. AntkowiakChristopher A. MoskalukSong HuFrederick H. EpsteinKimberly A. KellyNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael F. Gutknecht Marc E. Seaman Bo Ning Daniel Auger Cornejo Emily Mugler Patrick F. Antkowiak Christopher A. Moskaluk Song Hu Frederick H. Epstein Kimberly A. Kelly Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity
description	Angiogenesis is essential for solid tumor progression. Here, the authors interrogate the proteome of pancreatic cancer endothelium via phage display and identify hornerin as a critical protein whose expression is essential to maintain the pancreatic cancer vasculature through a VEGF-independent mechanism.
format	article
author	Michael F. Gutknecht Marc E. Seaman Bo Ning Daniel Auger Cornejo Emily Mugler Patrick F. Antkowiak Christopher A. Moskaluk Song Hu Frederick H. Epstein Kimberly A. Kelly
author_facet	Michael F. Gutknecht Marc E. Seaman Bo Ning Daniel Auger Cornejo Emily Mugler Patrick F. Antkowiak Christopher A. Moskaluk Song Hu Frederick H. Epstein Kimberly A. Kelly
author_sort	Michael F. Gutknecht
title	Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity
title_short	Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity
title_full	Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity
title_fullStr	Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity
title_full_unstemmed	Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity
title_sort	identification of the s100 fused-type protein hornerin as a regulator of tumor vascularity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/968ae9dba40541f79ec82b4f597514db
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Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity

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