Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity

Angiogenesis is essential for solid tumor progression. Here, the authors interrogate the proteome of pancreatic cancer endothelium via phage display and identify hornerin as a critical protein whose expression is essential to maintain the pancreatic cancer vasculature through a VEGF-independent mech...

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Autores principales: Michael F. Gutknecht, Marc E. Seaman, Bo Ning, Daniel Auger Cornejo, Emily Mugler, Patrick F. Antkowiak, Christopher A. Moskaluk, Song Hu, Frederick H. Epstein, Kimberly A. Kelly
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/968ae9dba40541f79ec82b4f597514db
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