Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid

Metformin is one of the most effective drugs for the treatment of type II diabetes. Two new mixed ligand complexes of vanadyl(ii) and chromium(iii) ions with the general formula [VOL1L2]SO4 and [CrL1L2(Cl)2]Cl, respectively, where L1 is the metformin and L2 is the glycine amino acid, have been synth...

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Autor principal:	Aljazzar Samar O.
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	metformin glycine mixed ligand complex vo(ii) ion cr(iii) ion Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/9698dcee78a1417b9a15b58c9b2b5219
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spelling	oai:doaj.org-article:9698dcee78a1417b9a15b58c9b2b52192021-12-05T14:10:44ZSynthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid2391-542010.1515/chem-2021-0063https://doaj.org/article/9698dcee78a1417b9a15b58c9b2b52192021-06-01T00:00:00Zhttps://doi.org/10.1515/chem-2021-0063https://doaj.org/toc/2391-5420Metformin is one of the most effective drugs for the treatment of type II diabetes. Two new mixed ligand complexes of vanadyl(ii) and chromium(iii) ions with the general formula [VOL1L2]SO4 and [CrL1L2(Cl)2]Cl, respectively, where L1 is the metformin and L2 is the glycine amino acid, have been synthesized in MeOH solvent with 1:1:1 stoichiometry and characterized by several spectroscopic techniques. The spectroscopic data suggested that the [VOL1L2]SO4 complex possesses a square pyramidal geometry, where the [CrL1L2(Cl)2]Cl complex possesses an octahedral geometry. The L1 ligand coordinated to the VO(ii) and Cr(iii) ions via the N atoms of the imino (‒C═NH) groups, where the L2 ligand coordinated via the O atom of the carboxylate group (COO) and the N atom of the amino group (NH2). The interaction of ligands L1 and L2 with the metal ions leads to complexes that have organized nanoscale structures with a main diameter of ∼14 nm for the [CrL1L2(Cl)2]Cl complex and ∼40 nm for the [VOL1L2]SO4 complex.Aljazzar Samar O.De Gruyterarticlemetforminglycinemixed ligand complexvo(ii) ioncr(iii) ionChemistryQD1-999ENOpen Chemistry, Vol 19, Iss 1, Pp 735-744 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	metformin glycine mixed ligand complex vo(ii) ion cr(iii) ion Chemistry QD1-999
spellingShingle	metformin glycine mixed ligand complex vo(ii) ion cr(iii) ion Chemistry QD1-999 Aljazzar Samar O. Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid
description	Metformin is one of the most effective drugs for the treatment of type II diabetes. Two new mixed ligand complexes of vanadyl(ii) and chromium(iii) ions with the general formula [VOL1L2]SO4 and [CrL1L2(Cl)2]Cl, respectively, where L1 is the metformin and L2 is the glycine amino acid, have been synthesized in MeOH solvent with 1:1:1 stoichiometry and characterized by several spectroscopic techniques. The spectroscopic data suggested that the [VOL1L2]SO4 complex possesses a square pyramidal geometry, where the [CrL1L2(Cl)2]Cl complex possesses an octahedral geometry. The L1 ligand coordinated to the VO(ii) and Cr(iii) ions via the N atoms of the imino (‒C═NH) groups, where the L2 ligand coordinated via the O atom of the carboxylate group (COO) and the N atom of the amino group (NH2). The interaction of ligands L1 and L2 with the metal ions leads to complexes that have organized nanoscale structures with a main diameter of ∼14 nm for the [CrL1L2(Cl)2]Cl complex and ∼40 nm for the [VOL1L2]SO4 complex.
format	article
author	Aljazzar Samar O.
author_facet	Aljazzar Samar O.
author_sort	Aljazzar Samar O.
title	Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid
title_short	Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid
title_full	Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid
title_fullStr	Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid
title_full_unstemmed	Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid
title_sort	synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/9698dcee78a1417b9a15b58c9b2b5219
work_keys_str_mv	AT aljazzarsamaro synthesisandspectralcharacterizationsofvanadyliiandchromiumiiimixedligandcomplexescontainingmetformindrugandglycineaminoacid
_version_	1718371797761523712

Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid

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