Tick-Borne Encephalitis Virus Vaccine-Induced Human Antibodies Mediate Negligible Enhancement of Zika Virus Infection <italic toggle="yes">In</italic> <italic toggle="yes">Vitro</italic> and in a Mouse Model

Tick-Borne Encephalitis Virus Vaccine-Induced Human Antibodies Mediate Negligible Enhancement of Zika Virus Infection <italic toggle="yes">In</italic> <italic toggle="yes">Vitro</italic> and in a Mouse Model

ABSTRACT Recent reports in the scientific literature have suggested that anti-dengue virus (DENV) and anti-West Nile virus (WNV) immunity exacerbates Zika virus (ZIKV) pathogenesis in vitro and in vivo in mouse models. Large populations of immune individuals exist for a related flavivirus (tick-born...

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Main Authors: James Duehr, Silviana Lee, Gursewak Singh, Gregory A. Foster, David Krysztof, Susan L. Stramer, Maria C. Bermúdez González, Eva Menichetti, Robert Geretschläger, Christian Gabriel, Viviana Simon, Jean K. Lim, Florian Krammer
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
ADE
TBEV
Zika
antibody-dependent enhancement
tick-borne encephalitis virus
Microbiology
QR1-502
Online Access:https://doaj.org/article/9698ef8dc1f74d87b7450f2a0d3ba7f5
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https://doaj.org/article/9698ef8dc1f74d87b7450f2a0d3ba7f5

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