Lysine acetylation regulates the interaction between proteins and membranes

Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates the function of membrane proteins. Here, the authors map lysine acetylation predominantly in membrane-interaction regions in peripheral membrane proteins and...

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Autores principales: Alan K. Okada, Kazuki Teranishi, Mark R. Ambroso, Jose Mario Isas, Elena Vazquez-Sarandeses, Joo-Yeun Lee, Arthur Alves Melo, Priyatama Pandey, Daniel Merken, Leona Berndt, Michael Lammers, Oliver Daumke, Karen Chang, Ian S. Haworth, Ralf Langen
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/969a6247f4f548d799fa269799855a27
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spelling oai:doaj.org-article:969a6247f4f548d799fa269799855a272021-11-14T12:35:43ZLysine acetylation regulates the interaction between proteins and membranes10.1038/s41467-021-26657-22041-1723https://doaj.org/article/969a6247f4f548d799fa269799855a272021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26657-2https://doaj.org/toc/2041-1723Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates the function of membrane proteins. Here, the authors map lysine acetylation predominantly in membrane-interaction regions in peripheral membrane proteins and show with three candidate proteins how lysine acetylation is a regulator of membrane protein function.Alan K. OkadaKazuki TeranishiMark R. AmbrosoJose Mario IsasElena Vazquez-SarandesesJoo-Yeun LeeArthur Alves MeloPriyatama PandeyDaniel MerkenLeona BerndtMichael LammersOliver DaumkeKaren ChangIan S. HaworthRalf LangenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alan K. Okada
Kazuki Teranishi
Mark R. Ambroso
Jose Mario Isas
Elena Vazquez-Sarandeses
Joo-Yeun Lee
Arthur Alves Melo
Priyatama Pandey
Daniel Merken
Leona Berndt
Michael Lammers
Oliver Daumke
Karen Chang
Ian S. Haworth
Ralf Langen
Lysine acetylation regulates the interaction between proteins and membranes
description Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates the function of membrane proteins. Here, the authors map lysine acetylation predominantly in membrane-interaction regions in peripheral membrane proteins and show with three candidate proteins how lysine acetylation is a regulator of membrane protein function.
format article
author Alan K. Okada
Kazuki Teranishi
Mark R. Ambroso
Jose Mario Isas
Elena Vazquez-Sarandeses
Joo-Yeun Lee
Arthur Alves Melo
Priyatama Pandey
Daniel Merken
Leona Berndt
Michael Lammers
Oliver Daumke
Karen Chang
Ian S. Haworth
Ralf Langen
author_facet Alan K. Okada
Kazuki Teranishi
Mark R. Ambroso
Jose Mario Isas
Elena Vazquez-Sarandeses
Joo-Yeun Lee
Arthur Alves Melo
Priyatama Pandey
Daniel Merken
Leona Berndt
Michael Lammers
Oliver Daumke
Karen Chang
Ian S. Haworth
Ralf Langen
author_sort Alan K. Okada
title Lysine acetylation regulates the interaction between proteins and membranes
title_short Lysine acetylation regulates the interaction between proteins and membranes
title_full Lysine acetylation regulates the interaction between proteins and membranes
title_fullStr Lysine acetylation regulates the interaction between proteins and membranes
title_full_unstemmed Lysine acetylation regulates the interaction between proteins and membranes
title_sort lysine acetylation regulates the interaction between proteins and membranes
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/969a6247f4f548d799fa269799855a27
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