Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review

Nephrotic syndrome (NS) can be a symptom of many autoimmune, metabolic, or infectious diseases. Kidney involvement is often observed in the course of diabetes mellitus (DM) and systemic lupus erythematosus (SLE). The development of NS with coexisting SLE and DM generates serious diagnostic problems....

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Autores principales:	Aleksandra Graca, Dorota Suszek, Radosław Jeleniewicz, Maria Majdan
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2020
Materias:	nephrotic syndrome diabetes mellitus type 1 systemic lupus erythematosus. Medicine R
Acceso en línea:	https://doaj.org/article/969df6f2e0e64700a601d91fcb86a664
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spelling	oai:doaj.org-article:969df6f2e0e64700a601d91fcb86a6642021-12-02T18:54:24ZNephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review0034-62332084-983410.5114/reum.2020.100105https://doaj.org/article/969df6f2e0e64700a601d91fcb86a6642020-10-01T00:00:00Zhttps://www.termedia.pl/Nephrotic-syndrome-in-the-course-of-type-1-diabetes-mellitus-and-systemic-lupus-erythematosus-with-secondary-antiphospholipid-syndrome-diagnostic-and-therapeutic-problems-A-case-based-review,18,42144,1,1.htmlhttps://doaj.org/toc/0034-6233https://doaj.org/toc/2084-9834Nephrotic syndrome (NS) can be a symptom of many autoimmune, metabolic, or infectious diseases. Kidney involvement is often observed in the course of diabetes mellitus (DM) and systemic lupus erythematosus (SLE). The development of NS with coexisting SLE and DM generates serious diagnostic problems. In this paper, the authors present diagnostic and therapeutic dilemmas in a patient with long-lasting DM, SLE, and secondary antiphospholipid syndrome, in whom NS symptoms appeared. Histopathological examination of the kidney confirmed the diagnosis of lupus nephritis. Immunosuppressive and anticoagulant drugs were used. The authors demonstrated that the character of morphologic lesions in the kidney biopsy can help in diagnosis, nephropathy classification, and further therapeutic decisions, which are distinct in both diseases.Aleksandra GracaDorota SuszekRadosław JeleniewiczMaria MajdanTermedia Publishing Housearticlenephrotic syndrome diabetes mellitus type 1 systemic lupus erythematosus.MedicineRENRheumatology, Vol 58, Iss 5, Pp 331-334 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	nephrotic syndrome diabetes mellitus type 1 systemic lupus erythematosus. Medicine R
spellingShingle	nephrotic syndrome diabetes mellitus type 1 systemic lupus erythematosus. Medicine R Aleksandra Graca Dorota Suszek Radosław Jeleniewicz Maria Majdan Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review
description	Nephrotic syndrome (NS) can be a symptom of many autoimmune, metabolic, or infectious diseases. Kidney involvement is often observed in the course of diabetes mellitus (DM) and systemic lupus erythematosus (SLE). The development of NS with coexisting SLE and DM generates serious diagnostic problems. In this paper, the authors present diagnostic and therapeutic dilemmas in a patient with long-lasting DM, SLE, and secondary antiphospholipid syndrome, in whom NS symptoms appeared. Histopathological examination of the kidney confirmed the diagnosis of lupus nephritis. Immunosuppressive and anticoagulant drugs were used. The authors demonstrated that the character of morphologic lesions in the kidney biopsy can help in diagnosis, nephropathy classification, and further therapeutic decisions, which are distinct in both diseases.
format	article
author	Aleksandra Graca Dorota Suszek Radosław Jeleniewicz Maria Majdan
author_facet	Aleksandra Graca Dorota Suszek Radosław Jeleniewicz Maria Majdan
author_sort	Aleksandra Graca
title	Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review
title_short	Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review
title_full	Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review
title_fullStr	Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review
title_full_unstemmed	Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review
title_sort	nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. a case-based review
publisher	Termedia Publishing House
publishDate	2020
url	https://doaj.org/article/969df6f2e0e64700a601d91fcb86a664
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Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review

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