Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells
The global health burden due to sepsis and the associated cytokine storm is substantial. While early intervention has improved survival during the cytokine storm, those that survive can enter a state of chronic immunoparalysis defined by transient lymphopenia and functional deficits of surviving cel...
Enregistré dans:
Auteurs principaux: | Isaac J Jensen, Xiang Li, Patrick W McGonagill, Qiang Shan, Micaela G Fosdick, Mikaela M Tremblay, Jon CD Houtman, Hai-Hui Xue, Thomas S Griffith, Weiqun Peng, Vladimir P Badovinac |
---|---|
Format: | article |
Langue: | EN |
Publié: |
eLife Sciences Publications Ltd
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/96b44fa8eb9b49b08945650bd27d9fdc |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
HOMEOSTATC PROLIFERATION AS A BASIS FOR THE INEVITABLE FORMATION OF TOTAL IMMUNODEFICIENCY
par: V. A. Kozlov
Publié: (2014) -
PROPORTION OF NAIVE CD45RA+ AND CD31+T-CELLS IN PATIENTS WITH RHEUMATOID ARTHRITIS UNDER STIMULATION WITH HOMEOSTATIC FACTORS IN VITRO
par: E. A. Blinova, et autres
Publié: (2021) -
LYMPHOPENIA AS A FACTOR INVOLVED IN THE AUTOIMMUNITY DEVELOPMENT IN MURINE GRAFT VS. HOST DISEASE
par: E. V. Goiman, et autres
Publié: (2012) -
T cell thymic selection and peripheral homeostatic proliferation in infectious diseases
par: V. A. Kozlov
Publié: (2020) -
INFLUENCE OF HOMEOSTATIC CYTOKINES – IL-7 AND IL-15 ON T-REGULATORY CELLS IN VITRO
par: D. V. Shevyrev, et autres
Publié: (2021)