Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report
Zui Narita,1 Harumasa Takano,1 Tomiki Sumiyoshi2 1Department of Psychiatry, National Center Hospital, 2Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, Japan Abstract: Neuromyelitis optica (NMO) is a relapsing disease that typic...
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2017
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oai:doaj.org-article:96bbde8a6da74501ad7b64be14c4c66f2021-12-02T02:55:28ZSuccessful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report1178-2021https://doaj.org/article/96bbde8a6da74501ad7b64be14c4c66f2017-03-01T00:00:00Zhttps://www.dovepress.com/successful-treatment-for-psychomotor-agitation-in-neuromyelitis-optica-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Zui Narita,1 Harumasa Takano,1 Tomiki Sumiyoshi2 1Department of Psychiatry, National Center Hospital, 2Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, Japan Abstract: Neuromyelitis optica (NMO) is a relapsing disease that typically affects the spinal cord and optic nerves. So far, a few studies have reported pharmacologic treatment for psychiatric symptoms in patients with NMO spectrum disorder (NMOSD). However, no literature has described psychomotor agitation associated with the disease and its treatment. We report an 84-year-old woman with NMOSD whose psychomotor agitation was effectively treated with a combination of trazodone and risperidone. Our observation suggests the ability of augmentation of antipsychotic drugs with antidepressants to ameliorate psychotic symptoms associated with NMOSD. Keywords: neuromyelitis optica, multiple sclerosis, psychomotor agitation, trazodone, risperidoneNarita ZTakano HSumiyoshi TDove Medical PressarticleNeuromyelitis opticaMultiple sclerosisPsychomotor agitationTrazodoneRisperidoneNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 13, Pp 775-777 (2017) |
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Neuromyelitis optica Multiple sclerosis Psychomotor agitation Trazodone Risperidone Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neuromyelitis optica Multiple sclerosis Psychomotor agitation Trazodone Risperidone Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Narita Z Takano H Sumiyoshi T Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report |
| description |
Zui Narita,1 Harumasa Takano,1 Tomiki Sumiyoshi2 1Department of Psychiatry, National Center Hospital, 2Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, Japan Abstract: Neuromyelitis optica (NMO) is a relapsing disease that typically affects the spinal cord and optic nerves. So far, a few studies have reported pharmacologic treatment for psychiatric symptoms in patients with NMO spectrum disorder (NMOSD). However, no literature has described psychomotor agitation associated with the disease and its treatment. We report an 84-year-old woman with NMOSD whose psychomotor agitation was effectively treated with a combination of trazodone and risperidone. Our observation suggests the ability of augmentation of antipsychotic drugs with antidepressants to ameliorate psychotic symptoms associated with NMOSD. Keywords: neuromyelitis optica, multiple sclerosis, psychomotor agitation, trazodone, risperidone |
| format |
article |
| author |
Narita Z Takano H Sumiyoshi T |
| author_facet |
Narita Z Takano H Sumiyoshi T |
| author_sort |
Narita Z |
| title |
Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report |
| title_short |
Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report |
| title_full |
Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report |
| title_fullStr |
Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report |
| title_full_unstemmed |
Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report |
| title_sort |
successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report |
| publisher |
Dove Medical Press |
| publishDate |
2017 |
| url |
https://doaj.org/article/96bbde8a6da74501ad7b64be14c4c66f |
| work_keys_str_mv |
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| _version_ |
1718402058613161984 |