Associations between measurements of central blood pressure and target organ damage in high-risk patients

Abstract Background It is not well-known which components of central blood pressure (CBP) are more influential to target organ damage (TOD). This study aimed to determine the relationship between CBP measurements and various types of TOD in high-risk patients. Methods A total of 148 patients who had...

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Autores principales:	Ki-Hyun Jeon, Hack-Lyoung Kim, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Aortic blood pressure Arterial pressure Atherosclerosis Hypertension Pulse pressure Medicine R Internal medicine RC31-1245
Acceso en línea:	https://doaj.org/article/96d7af90ee464dde99065edcaa6dc37d
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spelling	oai:doaj.org-article:96d7af90ee464dde99065edcaa6dc37d2021-12-05T12:21:04ZAssociations between measurements of central blood pressure and target organ damage in high-risk patients10.1186/s40885-021-00179-x2056-5909https://doaj.org/article/96d7af90ee464dde99065edcaa6dc37d2021-12-01T00:00:00Zhttps://doi.org/10.1186/s40885-021-00179-xhttps://doaj.org/toc/2056-5909Abstract Background It is not well-known which components of central blood pressure (CBP) are more influential to target organ damage (TOD). This study aimed to determine the relationship between CBP measurements and various types of TOD in high-risk patients. Methods A total of 148 patients who had documented atherosclerotic cardiovascular disease or its multiple risk factors were prospectively enrolled. CBP was measured by using applanation tonometry of the radial artery. The following nine TOD parameters were evaluated: left ventricular mass index, relative wall thickness, septal e′ velocity, septal E/e′, brachial-ankle pulse wave velocity, ankle-brachial index, estimated glomerular filtration rate, urine protein and obstructive coronary artery disease. Results The mean age of the study population was 67.1 ± 9.0 years and 108 (73 %) were male. Among four CBP measurements (systolic, diastolic, mean, and pulse pressures), central pulse pressure (CPP) was associated with the largest number of TOD parameters. As CPP increased, the number of TOD increased (P = 0.010), but this association was not observed in other CBP measurements (P > 0.05 for each). Conclusions CPP had a stronger correlation with TOD than other CBP measurements. Non-invasive CPP could be a useful indicator for predicting TOD in patients at high coronary risk.Ki-Hyun JeonHack-Lyoung KimWoo-Hyun LimJae-Bin SeoSang-Hyun KimJoo-Hee ZoMyung-A KimBMCarticleAortic blood pressureArterial pressureAtherosclerosisHypertensionPulse pressureMedicineRInternal medicineRC31-1245ENClinical Hypertension, Vol 27, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Aortic blood pressure Arterial pressure Atherosclerosis Hypertension Pulse pressure Medicine R Internal medicine RC31-1245
spellingShingle	Aortic blood pressure Arterial pressure Atherosclerosis Hypertension Pulse pressure Medicine R Internal medicine RC31-1245 Ki-Hyun Jeon Hack-Lyoung Kim Woo-Hyun Lim Jae-Bin Seo Sang-Hyun Kim Joo-Hee Zo Myung-A Kim Associations between measurements of central blood pressure and target organ damage in high-risk patients
description	Abstract Background It is not well-known which components of central blood pressure (CBP) are more influential to target organ damage (TOD). This study aimed to determine the relationship between CBP measurements and various types of TOD in high-risk patients. Methods A total of 148 patients who had documented atherosclerotic cardiovascular disease or its multiple risk factors were prospectively enrolled. CBP was measured by using applanation tonometry of the radial artery. The following nine TOD parameters were evaluated: left ventricular mass index, relative wall thickness, septal e′ velocity, septal E/e′, brachial-ankle pulse wave velocity, ankle-brachial index, estimated glomerular filtration rate, urine protein and obstructive coronary artery disease. Results The mean age of the study population was 67.1 ± 9.0 years and 108 (73 %) were male. Among four CBP measurements (systolic, diastolic, mean, and pulse pressures), central pulse pressure (CPP) was associated with the largest number of TOD parameters. As CPP increased, the number of TOD increased (P = 0.010), but this association was not observed in other CBP measurements (P > 0.05 for each). Conclusions CPP had a stronger correlation with TOD than other CBP measurements. Non-invasive CPP could be a useful indicator for predicting TOD in patients at high coronary risk.
format	article
author	Ki-Hyun Jeon Hack-Lyoung Kim Woo-Hyun Lim Jae-Bin Seo Sang-Hyun Kim Joo-Hee Zo Myung-A Kim
author_facet	Ki-Hyun Jeon Hack-Lyoung Kim Woo-Hyun Lim Jae-Bin Seo Sang-Hyun Kim Joo-Hee Zo Myung-A Kim
author_sort	Ki-Hyun Jeon
title	Associations between measurements of central blood pressure and target organ damage in high-risk patients
title_short	Associations between measurements of central blood pressure and target organ damage in high-risk patients
title_full	Associations between measurements of central blood pressure and target organ damage in high-risk patients
title_fullStr	Associations between measurements of central blood pressure and target organ damage in high-risk patients
title_full_unstemmed	Associations between measurements of central blood pressure and target organ damage in high-risk patients
title_sort	associations between measurements of central blood pressure and target organ damage in high-risk patients
publisher	BMC
publishDate	2021
url	https://doaj.org/article/96d7af90ee464dde99065edcaa6dc37d
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Associations between measurements of central blood pressure and target organ damage in high-risk patients

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