A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor

The LEAFY transcription factor is a master regulator of flower development in plants. Here the authors describe the structure of a LEAFY oligomerization domain and show that mutations that disrupt oligomerization alter its capacity to bind low affinity and poorly accessible target sites.

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Autores principales:	Camille Sayou, Max H. Nanao, Marc Jamin, David Posé, Emmanuel Thévenon, Laura Grégoire, Gabrielle Tichtinsky, Grégoire Denay, Felix Ott, Marta Peirats Llobet, Markus Schmid, Renaud Dumas, François Parcy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/96d83391804042f59f93135fd8d1bacb
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spelling	oai:doaj.org-article:96d83391804042f59f93135fd8d1bacb2021-12-02T16:49:58ZA SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor10.1038/ncomms112222041-1723https://doaj.org/article/96d83391804042f59f93135fd8d1bacb2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11222https://doaj.org/toc/2041-1723The LEAFY transcription factor is a master regulator of flower development in plants. Here the authors describe the structure of a LEAFY oligomerization domain and show that mutations that disrupt oligomerization alter its capacity to bind low affinity and poorly accessible target sites.Camille SayouMax H. NanaoMarc JaminDavid PoséEmmanuel ThévenonLaura GrégoireGabrielle TichtinskyGrégoire DenayFelix OttMarta Peirats LlobetMarkus SchmidRenaud DumasFrançois ParcyNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Camille Sayou Max H. Nanao Marc Jamin David Posé Emmanuel Thévenon Laura Grégoire Gabrielle Tichtinsky Grégoire Denay Felix Ott Marta Peirats Llobet Markus Schmid Renaud Dumas François Parcy A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor
description	The LEAFY transcription factor is a master regulator of flower development in plants. Here the authors describe the structure of a LEAFY oligomerization domain and show that mutations that disrupt oligomerization alter its capacity to bind low affinity and poorly accessible target sites.
format	article
author	Camille Sayou Max H. Nanao Marc Jamin David Posé Emmanuel Thévenon Laura Grégoire Gabrielle Tichtinsky Grégoire Denay Felix Ott Marta Peirats Llobet Markus Schmid Renaud Dumas François Parcy
author_facet	Camille Sayou Max H. Nanao Marc Jamin David Posé Emmanuel Thévenon Laura Grégoire Gabrielle Tichtinsky Grégoire Denay Felix Ott Marta Peirats Llobet Markus Schmid Renaud Dumas François Parcy
author_sort	Camille Sayou
title	A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor
title_short	A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor
title_full	A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor
title_fullStr	A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor
title_full_unstemmed	A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor
title_sort	sam oligomerization domain shapes the genomic binding landscape of the leafy transcription factor
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/96d83391804042f59f93135fd8d1bacb
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A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor

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