Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits

Rare structural variants may account for a significant fraction of variation in complex traits. Here the authors analyse 14 Drosophila melanogaster genomes and find that structural variants are common, found in functionally important genes, and associated with QTLs.

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Autores principales: Mahul Chakraborty, J. J. Emerson, Stuart J. Macdonald, Anthony D. Long
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/96ea71b67269422fb3fcaaf4399db70f
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