Regioselective synthesis of C3 alkylated and arylated benzothiophenes
Benzothiophenes are common motifs in bioactive compounds, but selective functionalization at C3 is challenging. Here the authors report a method starting from benzothiophene S-oxides via an interrupted Pummerer reaction, giving access to a range of C3-alkylated and -arylated products.
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/96ecf75c80164e3692bef7fa44f24f7a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!