Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

Abstract Amyloid β (Aβ) oligomers may play a decisive role in Alzheimer’s disease related neurodegeneration, but their structural properties are poorly understood. In this report, sedimentation velocity centrifugation, small angle neutron scattering (SANS) and molecular modelling were used to identi...

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Autores principales: Martin Wolff, Bo Zhang-Haagen, Christina Decker, Bogdan Barz, Mario Schneider, Ralf Biehl, Aurel Radulescu, Birgit Strodel, Dieter Willbold, Luitgard Nagel-Steger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/96f163f4a72e4c548032532f4e1748db
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