Controlling protein activity by dynamic recruitment on a supramolecular polymer platform
DNA-origami allows the precise recruitment of DNA-protein conjugates but lacks the dynamics found in natural protein assemblies. Here the authors present a synthetic polymer platform that combines the dynamics of supramolecular polymers with the programmability of DNA-mediated protein recruitment.
Enregistré dans:
Auteurs principaux: | Sjors P. W. Wijnands, Wouter Engelen, René P. M. Lafleur, E. W. Meijer, Maarten Merkx |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/96f21eff2c8d4ad2bfb01b1a20c40bed |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Dynamic diversity of synthetic supramolecular polymers in water as revealed by hydrogen/deuterium exchange
par: Xianwen Lou, et autres
Publié: (2017) -
Antibody-controlled actuation of DNA-based molecular circuits
par: Wouter Engelen, et autres
Publié: (2017) -
Into the Dynamics of a Supramolecular Polymer at Submolecular Resolution
par: Davide Bochicchio, et autres
Publié: (2017) -
Optically responsive supramolecular polymer glasses
par: Diederik W. R. Balkenende, et autres
Publié: (2016) -
Hierarchical control of enzymatic actuators using DNA-based switchable memories
par: Lenny H. H. Meijer, et autres
Publié: (2017)