Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia

Abstract The emergence of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2) and its complications have demonstrated the devastating impact of a new infectious pathogen. The organisational change promulgated by the isolation of affected communities is of extreme importance to achieve...

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Autores principales:	Marco Bassanello, Luciano Pasini, Marco Senzolo, Andrea Gambaro, Marco Roman, Ugo Coli, Maurizio D’Aquino
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/96f3d4b97b5f462b82503ba7396a7c71
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spelling	oai:doaj.org-article:96f3d4b97b5f462b82503ba7396a7c712021-12-05T12:12:31ZEpidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia10.1038/s41598-021-02654-92045-2322https://doaj.org/article/96f3d4b97b5f462b82503ba7396a7c712021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02654-9https://doaj.org/toc/2045-2322Abstract The emergence of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2) and its complications have demonstrated the devastating impact of a new infectious pathogen. The organisational change promulgated by the isolation of affected communities is of extreme importance to achieve effective containment of the contagion and good patient care. The epidemiological study of the population of a small rural community in the North East of Italy revealed how much the virus had circulated during Spring, 2020, and how contagion has evolved after a prolonged lockdown. In the 1st phase, NAAT (Nucleic Acid Amplification Testing) was performed in cases with more or less severe symptoms and a study was performed to trace the infection of family members. Only 0.2% of the population tested positive on NAAT, via nasopharyngeal swab during this 1st phase. In the 2nd phase a random sample of the general population were tested for circulating anti-Sars-Cov-2 immunoglobulins. This showed that approximately 97.9% of the population were negative, while 2.1% (with positive IgG at a distance) of the population had contracted the virus in a mildly symptomatic or asymptomatic form. The main symptom in subjects who developed immunity was fever. Antibodies were found in subjects with forced coexistence with quarantined or infected subjects. The mutual spatial distance by categories has shown higher relative prevalence of IgG positive and IgM negative cases in close proximity but also far from the infected, with respect to an intermediate distance. This suggests that subjects living in thinly populated areas could come in contact with the virus more likely due to intentional/relational proximity, while those living nearby could also be infected through random proximity.Marco BassanelloLuciano PasiniMarco SenzoloAndrea GambaroMarco RomanUgo ColiMaurizio D’AquinoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Marco Bassanello Luciano Pasini Marco Senzolo Andrea Gambaro Marco Roman Ugo Coli Maurizio D’Aquino Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia
description	Abstract The emergence of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2) and its complications have demonstrated the devastating impact of a new infectious pathogen. The organisational change promulgated by the isolation of affected communities is of extreme importance to achieve effective containment of the contagion and good patient care. The epidemiological study of the population of a small rural community in the North East of Italy revealed how much the virus had circulated during Spring, 2020, and how contagion has evolved after a prolonged lockdown. In the 1st phase, NAAT (Nucleic Acid Amplification Testing) was performed in cases with more or less severe symptoms and a study was performed to trace the infection of family members. Only 0.2% of the population tested positive on NAAT, via nasopharyngeal swab during this 1st phase. In the 2nd phase a random sample of the general population were tested for circulating anti-Sars-Cov-2 immunoglobulins. This showed that approximately 97.9% of the population were negative, while 2.1% (with positive IgG at a distance) of the population had contracted the virus in a mildly symptomatic or asymptomatic form. The main symptom in subjects who developed immunity was fever. Antibodies were found in subjects with forced coexistence with quarantined or infected subjects. The mutual spatial distance by categories has shown higher relative prevalence of IgG positive and IgM negative cases in close proximity but also far from the infected, with respect to an intermediate distance. This suggests that subjects living in thinly populated areas could come in contact with the virus more likely due to intentional/relational proximity, while those living nearby could also be infected through random proximity.
format	article
author	Marco Bassanello Luciano Pasini Marco Senzolo Andrea Gambaro Marco Roman Ugo Coli Maurizio D’Aquino
author_facet	Marco Bassanello Luciano Pasini Marco Senzolo Andrea Gambaro Marco Roman Ugo Coli Maurizio D’Aquino
author_sort	Marco Bassanello
title	Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia
title_short	Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia
title_full	Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia
title_fullStr	Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia
title_full_unstemmed	Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia
title_sort	epidemiological study in a small rural area of veneto (italian region) during sars-cov-2 pandemia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/96f3d4b97b5f462b82503ba7396a7c71
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Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia

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