Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves

Abstract Sweet potato, Ipomoea batatas, is a widely cultivated vegetable worldwide. The leaves contain polyphenolic natural products called caffeoylquinic acids (CQAs), which possess biological activities including inhibition of aggregation of amyloid peptides. The present study describes an efficie...

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Main Authors:	Toyonobu Usuki, Shingo Onda, Masahiro Yoshizawa-Fujita, Masahiro Rikukawa
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Medicine R Science Q
Online Access:	https://doaj.org/article/96f9f06bddee4d39ad64f77c0757b58d
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spelling	oai:doaj.org-article:96f9f06bddee4d39ad64f77c0757b58d2021-12-02T16:06:22ZUse of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves10.1038/s41598-017-07291-92045-2322https://doaj.org/article/96f9f06bddee4d39ad64f77c0757b58d2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07291-9https://doaj.org/toc/2045-2322Abstract Sweet potato, Ipomoea batatas, is a widely cultivated vegetable worldwide. The leaves contain polyphenolic natural products called caffeoylquinic acids (CQAs), which possess biological activities including inhibition of aggregation of amyloid peptides. The present study describes an efficient extraction and isolation procedure for CQAs from sweet potato leaves using a cellulose-dissolving ionic liquid. The results showed that, compared to methanol, use of 1-butyl-3-methylimidazolium chloride ([C4mim]Cl) allowed the extraction of a 6.5-fold greater amount of CQAs. This protocol will enable the efficient extraction of other organic compounds and biopolymers from natural materials.Toyonobu UsukiShingo OndaMasahiro Yoshizawa-FujitaMasahiro RikukawaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Toyonobu Usuki Shingo Onda Masahiro Yoshizawa-Fujita Masahiro Rikukawa Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
description	Abstract Sweet potato, Ipomoea batatas, is a widely cultivated vegetable worldwide. The leaves contain polyphenolic natural products called caffeoylquinic acids (CQAs), which possess biological activities including inhibition of aggregation of amyloid peptides. The present study describes an efficient extraction and isolation procedure for CQAs from sweet potato leaves using a cellulose-dissolving ionic liquid. The results showed that, compared to methanol, use of 1-butyl-3-methylimidazolium chloride ([C4mim]Cl) allowed the extraction of a 6.5-fold greater amount of CQAs. This protocol will enable the efficient extraction of other organic compounds and biopolymers from natural materials.
format	article
author	Toyonobu Usuki Shingo Onda Masahiro Yoshizawa-Fujita Masahiro Rikukawa
author_facet	Toyonobu Usuki Shingo Onda Masahiro Yoshizawa-Fujita Masahiro Rikukawa
author_sort	Toyonobu Usuki
title	Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_short	Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_full	Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_fullStr	Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_full_unstemmed	Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_sort	use of [c4mim]cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/96f9f06bddee4d39ad64f77c0757b58d
work_keys_str_mv	AT toyonobuusuki useofc4mimclforefficientextractionofcaffeoylquinicacidsfromsweetpotatoleaves AT shingoonda useofc4mimclforefficientextractionofcaffeoylquinicacidsfromsweetpotatoleaves AT masahiroyoshizawafujita useofc4mimclforefficientextractionofcaffeoylquinicacidsfromsweetpotatoleaves AT masahirorikukawa useofc4mimclforefficientextractionofcaffeoylquinicacidsfromsweetpotatoleaves
_version_	1718385039500115968

Use of [C4mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves

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