Clinicopathological features and surgical treatment of cervical oesophageal cancer

Abstract Cervical oesophageal cancer (CEC) is a relatively uncommon malignancy. The biological behaviour and treatment have not been well studied. This retrospective study reviewed the clinicopathological features of 28 patients with CEC who underwent surgical resection to investigate the biological...

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Autores principales:	Shao-bin Chen, Xi-hong Yang, Hong-rui Weng, Di-tian Liu, Hua Li, Yu-ping Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/97005c00f89f4af1ac6a784b6edc2c5d
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spelling	oai:doaj.org-article:97005c00f89f4af1ac6a784b6edc2c5d2021-12-02T11:52:58ZClinicopathological features and surgical treatment of cervical oesophageal cancer10.1038/s41598-017-03593-02045-2322https://doaj.org/article/97005c00f89f4af1ac6a784b6edc2c5d2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-03593-0https://doaj.org/toc/2045-2322Abstract Cervical oesophageal cancer (CEC) is a relatively uncommon malignancy. The biological behaviour and treatment have not been well studied. This retrospective study reviewed the clinicopathological features of 28 patients with CEC who underwent surgical resection to investigate the biological behaviour, treatment and prognosis of CEC. The long-term outcomes of these patients were compared with those of the CEC patients who received definitive chemoradiotherapy and those of thoracic or abdominal oesophageal cancer patients who underwent surgery. The study group contained 21 men and 7 women, ranging in age from 41 to 67 years (median: 56.5 years). The median survival time and the 1-, 3-, and 5-year overall survival rates were 25.0 months, 83.8%, 48.8%, and 41.9%, respectively. Only salvage surgery was found to affect the overall survival (P = 0.007). The long-term outcomes for CEC patients who underwent surgery were significantly better than those who received definitive chemoradiotherapy (P = 0.045) but were similar to those of thoracic or abdominal oesophageal cancer patients. In summary, CEC is an uncommon and aggressive malignancy. The malignant potential of CEC is similar to that of thoracic or abdominal oesophageal cancer. Surgical resection is an important therapeutic strategy and may be associated with better survival rates than definitive chemoradiotherapy.Shao-bin ChenXi-hong YangHong-rui WengDi-tian LiuHua LiYu-ping ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shao-bin Chen Xi-hong Yang Hong-rui Weng Di-tian Liu Hua Li Yu-ping Chen Clinicopathological features and surgical treatment of cervical oesophageal cancer
description	Abstract Cervical oesophageal cancer (CEC) is a relatively uncommon malignancy. The biological behaviour and treatment have not been well studied. This retrospective study reviewed the clinicopathological features of 28 patients with CEC who underwent surgical resection to investigate the biological behaviour, treatment and prognosis of CEC. The long-term outcomes of these patients were compared with those of the CEC patients who received definitive chemoradiotherapy and those of thoracic or abdominal oesophageal cancer patients who underwent surgery. The study group contained 21 men and 7 women, ranging in age from 41 to 67 years (median: 56.5 years). The median survival time and the 1-, 3-, and 5-year overall survival rates were 25.0 months, 83.8%, 48.8%, and 41.9%, respectively. Only salvage surgery was found to affect the overall survival (P = 0.007). The long-term outcomes for CEC patients who underwent surgery were significantly better than those who received definitive chemoradiotherapy (P = 0.045) but were similar to those of thoracic or abdominal oesophageal cancer patients. In summary, CEC is an uncommon and aggressive malignancy. The malignant potential of CEC is similar to that of thoracic or abdominal oesophageal cancer. Surgical resection is an important therapeutic strategy and may be associated with better survival rates than definitive chemoradiotherapy.
format	article
author	Shao-bin Chen Xi-hong Yang Hong-rui Weng Di-tian Liu Hua Li Yu-ping Chen
author_facet	Shao-bin Chen Xi-hong Yang Hong-rui Weng Di-tian Liu Hua Li Yu-ping Chen
author_sort	Shao-bin Chen
title	Clinicopathological features and surgical treatment of cervical oesophageal cancer
title_short	Clinicopathological features and surgical treatment of cervical oesophageal cancer
title_full	Clinicopathological features and surgical treatment of cervical oesophageal cancer
title_fullStr	Clinicopathological features and surgical treatment of cervical oesophageal cancer
title_full_unstemmed	Clinicopathological features and surgical treatment of cervical oesophageal cancer
title_sort	clinicopathological features and surgical treatment of cervical oesophageal cancer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/97005c00f89f4af1ac6a784b6edc2c5d
work_keys_str_mv	AT shaobinchen clinicopathologicalfeaturesandsurgicaltreatmentofcervicaloesophagealcancer AT xihongyang clinicopathologicalfeaturesandsurgicaltreatmentofcervicaloesophagealcancer AT hongruiweng clinicopathologicalfeaturesandsurgicaltreatmentofcervicaloesophagealcancer AT ditianliu clinicopathologicalfeaturesandsurgicaltreatmentofcervicaloesophagealcancer AT huali clinicopathologicalfeaturesandsurgicaltreatmentofcervicaloesophagealcancer AT yupingchen clinicopathologicalfeaturesandsurgicaltreatmentofcervicaloesophagealcancer
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Clinicopathological features and surgical treatment of cervical oesophageal cancer

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