Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract

Tanner J Ferguson,1 John P Berdahl,2 Justin A Schweitzer,2 Ramu G Sudhagoni1 1Sanford School of Medicine, University of South Dakota, Sanford School of Medicine, Sioux Falls, SD, USA; 2Vance Thompson Vision, Sioux Falls, SD, USA Purpose: To evaluate the safety and efficacy of the iStent trabecular...

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Autores principales:	Ferguson TJ, Berdahl JP, Schweitzer JA, Sudhagoni RG
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	MIGS Microinvasive glaucoma surgery glaucoma iStent trabecular micro-bypass stent primary open angle glaucoma Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/97061349d3b349a9b85cc80c4a95188d
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spelling	oai:doaj.org-article:97061349d3b349a9b85cc80c4a95188d2021-12-02T04:40:43ZClinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract1177-5483https://doaj.org/article/97061349d3b349a9b85cc80c4a95188d2016-09-01T00:00:00Zhttps://www.dovepress.com/clinical-evaluation-of-a-trabecular-microbypass-stent-with-phacoemulsi-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Tanner J Ferguson,1 John P Berdahl,2 Justin A Schweitzer,2 Ramu G Sudhagoni1 1Sanford School of Medicine, University of South Dakota, Sanford School of Medicine, Sioux Falls, SD, USA; 2Vance Thompson Vision, Sioux Falls, SD, USA Purpose: To evaluate the safety and efficacy of the iStent trabecular microbypass stent in combination with cataract surgery in patients with open-angle glaucoma (OAG).Methods: Retrospective, consecutive case series from October 2012 to December 2015 with no exclusion criteria. The series comprised of 350 eyes with OAG and cataract. Data were collected both preoperatively and postoperatively at day 1 week 1, months 1, 3, 6, 12, 18, and 24. Data included intraocular pressure (IOP), number of glaucoma medications, visual acuity, the incidence of postoperative IOP pressure spikes of greater than ≥15 mmHg at any time point, and need for additional surgery.Results: The mean preoperative IOP was 19.13±6.34 mmHg. At 2 years postoperation, mean IOP was 15.17±3.53 mmHg (P<0.0001). The mean number of glaucoma medications was 1.19±1.00 preoperatively and 0.61±0.96 (P<0.0001) at 2 years postoperation. At 1 day postoperatively, 31 eyes (12.4%) experienced an IOP increase of 15 mmHg above their baseline IOP that responded to topical therapy. Two patients required additional tube shunt surgery.Conclusion: The insertion of the iStent trabecular microbypass stent in combination with cataract surgery effectively lowers IOP in OAG patients. The magnitude of IOP reduction was more significant in patients with higher preoperative pressure. Medication use was also significantly reduced postoperatively. The safety profile appears favorable with a low rate of IOP spikes and only two eyes (<1%) requiring additional surgery. Keywords: iStent, trabecular microbypass stent, glaucoma, microinvasive glaucoma surgery, open-angle glaucoma, glaucoma surgeryFerguson TJBerdahl JPSchweitzer JASudhagoni RGDove Medical PressarticleMIGSMicroinvasive glaucoma surgeryglaucomaiStenttrabecular micro-bypass stentprimary open angle glaucomaOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 10, Pp 1767-1773 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	MIGS Microinvasive glaucoma surgery glaucoma iStent trabecular micro-bypass stent primary open angle glaucoma Ophthalmology RE1-994
spellingShingle	MIGS Microinvasive glaucoma surgery glaucoma iStent trabecular micro-bypass stent primary open angle glaucoma Ophthalmology RE1-994 Ferguson TJ Berdahl JP Schweitzer JA Sudhagoni RG Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract
description	Tanner J Ferguson,1 John P Berdahl,2 Justin A Schweitzer,2 Ramu G Sudhagoni1 1Sanford School of Medicine, University of South Dakota, Sanford School of Medicine, Sioux Falls, SD, USA; 2Vance Thompson Vision, Sioux Falls, SD, USA Purpose: To evaluate the safety and efficacy of the iStent trabecular microbypass stent in combination with cataract surgery in patients with open-angle glaucoma (OAG).Methods: Retrospective, consecutive case series from October 2012 to December 2015 with no exclusion criteria. The series comprised of 350 eyes with OAG and cataract. Data were collected both preoperatively and postoperatively at day 1 week 1, months 1, 3, 6, 12, 18, and 24. Data included intraocular pressure (IOP), number of glaucoma medications, visual acuity, the incidence of postoperative IOP pressure spikes of greater than ≥15 mmHg at any time point, and need for additional surgery.Results: The mean preoperative IOP was 19.13±6.34 mmHg. At 2 years postoperation, mean IOP was 15.17±3.53 mmHg (P<0.0001). The mean number of glaucoma medications was 1.19±1.00 preoperatively and 0.61±0.96 (P<0.0001) at 2 years postoperation. At 1 day postoperatively, 31 eyes (12.4%) experienced an IOP increase of 15 mmHg above their baseline IOP that responded to topical therapy. Two patients required additional tube shunt surgery.Conclusion: The insertion of the iStent trabecular microbypass stent in combination with cataract surgery effectively lowers IOP in OAG patients. The magnitude of IOP reduction was more significant in patients with higher preoperative pressure. Medication use was also significantly reduced postoperatively. The safety profile appears favorable with a low rate of IOP spikes and only two eyes (<1%) requiring additional surgery. Keywords: iStent, trabecular microbypass stent, glaucoma, microinvasive glaucoma surgery, open-angle glaucoma, glaucoma surgery
format	article
author	Ferguson TJ Berdahl JP Schweitzer JA Sudhagoni RG
author_facet	Ferguson TJ Berdahl JP Schweitzer JA Sudhagoni RG
author_sort	Ferguson TJ
title	Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract
title_short	Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract
title_full	Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract
title_fullStr	Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract
title_full_unstemmed	Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract
title_sort	clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/97061349d3b349a9b85cc80c4a95188d
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Clinical evaluation of a trabecular microbypass stent with phacoemulsification in patients with open-angle glaucoma and cataract

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