Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives

Victoria L Fisher,1 Abd A Tahrani2–4 1School of Medicine, University of Nottingham, Nottingham, 2Institute of Metabolism and Systems Research, University of Birmingham, 3Department of Diabetes and Endocrinology, Birmingham Heartlands Hospital, 4Centre for Endocrinology, Diabetes and Metabo...

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Autores principales:	Fisher VL, Tahrani AA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Diabetes mellitus Cardiovascular Autonomic Neuropathy Autonomic neuropathy Cardiac Autonomic Neuropathy Orthostatic hypotension Postural hypotension Hyperglycemia Heart rate variability. Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/9706c1ac60824deca342fd154fd4886e
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spelling	oai:doaj.org-article:9706c1ac60824deca342fd154fd4886e2021-12-02T06:33:33ZCardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives1178-7007https://doaj.org/article/9706c1ac60824deca342fd154fd4886e2017-10-01T00:00:00Zhttps://www.dovepress.com/cardiac-autonomic-neuropathy-in-patients-with-diabetes-mellitus-curren-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Victoria L Fisher,1 Abd A Tahrani2–4 1School of Medicine, University of Nottingham, Nottingham, 2Institute of Metabolism and Systems Research, University of Birmingham, 3Department of Diabetes and Endocrinology, Birmingham Heartlands Hospital, 4Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK Abstract: Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite these significant consequences CAN often remains undiagnosed for a prolonged period. This is commonly due to the disease being asymptomatic until the later stages, as well as a lack of easily available screening strategies. In this article, we review the latest developments in the epidemiology, pathogenesis, diagnosis, consequences, and treatments of CAN in patients with DM. Keywords: cardiovascular, autonomic, neuropathy, orthostatic hypotension, postural hypotension, hyperglycemia, heart-rate variability, sympathetic, parasympathetic, deep breathing, Valsalva ratio, 30:15 ratio, Ewing tests, Ewing criteriaFisher VLTahrani AADove Medical PressarticleDiabetes mellitusCardiovascularAutonomicNeuropathyAutonomic neuropathyCardiac Autonomic NeuropathyOrthostatic hypotensionPostural hypotensionHyperglycemiaHeart rate variability.Specialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 10, Pp 419-434 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diabetes mellitus Cardiovascular Autonomic Neuropathy Autonomic neuropathy Cardiac Autonomic Neuropathy Orthostatic hypotension Postural hypotension Hyperglycemia Heart rate variability. Specialties of internal medicine RC581-951
spellingShingle	Diabetes mellitus Cardiovascular Autonomic Neuropathy Autonomic neuropathy Cardiac Autonomic Neuropathy Orthostatic hypotension Postural hypotension Hyperglycemia Heart rate variability. Specialties of internal medicine RC581-951 Fisher VL Tahrani AA Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
description	Victoria L Fisher,1 Abd A Tahrani2–4 1School of Medicine, University of Nottingham, Nottingham, 2Institute of Metabolism and Systems Research, University of Birmingham, 3Department of Diabetes and Endocrinology, Birmingham Heartlands Hospital, 4Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK Abstract: Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite these significant consequences CAN often remains undiagnosed for a prolonged period. This is commonly due to the disease being asymptomatic until the later stages, as well as a lack of easily available screening strategies. In this article, we review the latest developments in the epidemiology, pathogenesis, diagnosis, consequences, and treatments of CAN in patients with DM. Keywords: cardiovascular, autonomic, neuropathy, orthostatic hypotension, postural hypotension, hyperglycemia, heart-rate variability, sympathetic, parasympathetic, deep breathing, Valsalva ratio, 30:15 ratio, Ewing tests, Ewing criteria
format	article
author	Fisher VL Tahrani AA
author_facet	Fisher VL Tahrani AA
author_sort	Fisher VL
title	Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
title_short	Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
title_full	Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
title_fullStr	Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
title_full_unstemmed	Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
title_sort	cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/9706c1ac60824deca342fd154fd4886e
work_keys_str_mv	AT fishervl cardiacautonomicneuropathyinpatientswithdiabetesmellituscurrentperspectives AT tahraniaa cardiacautonomicneuropathyinpatientswithdiabetesmellituscurrentperspectives
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Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives

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