A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression but many quantitative aspects of miRNA biology remain to be elucidated. Based on a library of miRNA sensors, the authors quantify miRNA regulation at single cell level and develop a model to predict miRNA target inte...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jeremy J. Gam, Jonathan Babb, Ron Weiss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9713160e9e0b4de492ec105715c1bd3d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9713160e9e0b4de492ec105715c1bd3d
record_format	dspace
spelling	oai:doaj.org-article:9713160e9e0b4de492ec105715c1bd3d2021-12-02T15:34:00ZA mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity10.1038/s41467-018-04575-02041-1723https://doaj.org/article/9713160e9e0b4de492ec105715c1bd3d2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04575-0https://doaj.org/toc/2041-1723MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression but many quantitative aspects of miRNA biology remain to be elucidated. Based on a library of miRNA sensors, the authors quantify miRNA regulation at single cell level and develop a model to predict miRNA target interactions.Jeremy J. GamJonathan BabbRon WeissNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jeremy J. Gam Jonathan Babb Ron Weiss A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
description	MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression but many quantitative aspects of miRNA biology remain to be elucidated. Based on a library of miRNA sensors, the authors quantify miRNA regulation at single cell level and develop a model to predict miRNA target interactions.
format	article
author	Jeremy J. Gam Jonathan Babb Ron Weiss
author_facet	Jeremy J. Gam Jonathan Babb Ron Weiss
author_sort	Jeremy J. Gam
title	A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
title_short	A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
title_full	A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
title_fullStr	A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
title_full_unstemmed	A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
title_sort	mixed antagonistic/synergistic mirna repression model enables accurate predictions of multi-input mirna sensor activity
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9713160e9e0b4de492ec105715c1bd3d
work_keys_str_mv	AT jeremyjgam amixedantagonisticsynergisticmirnarepressionmodelenablesaccuratepredictionsofmultiinputmirnasensoractivity AT jonathanbabb amixedantagonisticsynergisticmirnarepressionmodelenablesaccuratepredictionsofmultiinputmirnasensoractivity AT ronweiss amixedantagonisticsynergisticmirnarepressionmodelenablesaccuratepredictionsofmultiinputmirnasensoractivity AT jeremyjgam mixedantagonisticsynergisticmirnarepressionmodelenablesaccuratepredictionsofmultiinputmirnasensoractivity AT jonathanbabb mixedantagonisticsynergisticmirnarepressionmodelenablesaccuratepredictionsofmultiinputmirnasensoractivity AT ronweiss mixedantagonisticsynergisticmirnarepressionmodelenablesaccuratepredictionsofmultiinputmirnasensoractivity
_version_	1718386978272051200

A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity

Ejemplares similares