Overweight, obesity and meningioma risk: a meta-analysis.

<h4>Background and objectives</h4>Studies of the association between excess body weight and risk of meningioma have produced inconsistent results. Therefore, a meta-analysis of published studies was performed to better assess the association between meningioma and excess body weight.<...

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Autores principales:	Chuan Shao, Li-Ping Bai, Zhen-Yu Qi, Guo-Zhen Hui, Zhong Wang
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9713de80aa9843c3ab625325036ee351
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spelling	oai:doaj.org-article:9713de80aa9843c3ab625325036ee3512021-11-18T08:30:48ZOverweight, obesity and meningioma risk: a meta-analysis.1932-620310.1371/journal.pone.0090167https://doaj.org/article/9713de80aa9843c3ab625325036ee3512014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24587258/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background and objectives</h4>Studies of the association between excess body weight and risk of meningioma have produced inconsistent results. Therefore, a meta-analysis of published studies was performed to better assess the association between meningioma and excess body weight.<h4>Methods</h4>A literature search was conducted in the PubMed and EMBASE databases without any limitations. The reference lists of identified articles were also screened for additional studies. The summary relative risks (RRs) and 95% confidence intervals (CI) were calculated using fixed- or random-effects models.<h4>Results</h4>A total of 6 studies provided risk estimates for overweight or obesity. Overall, the combined RRs were 1.12 (95% CI = 0.98-1.28) for overweight and 1.45 (95% CI = 1.26-1.67) for obesity. After stratification by gender, no significant association was observed for obese men (RR = 1.30, 95% CI = 0.64-2.62), while significant association was detected for obese women (RR = 1.46, 95% CI = 1.26-1.69). No substantial differences emerged across strata of study design and geographic areas.<h4>Conclusion</h4>The results of this meta-analysis suggest that obesity but not overweight is associated with an increased risk of meningioma. Due to the limited number of studies, further research is needed to confirm the association.Chuan ShaoLi-Ping BaiZhen-Yu QiGuo-Zhen HuiZhong WangPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 2, p e90167 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chuan Shao Li-Ping Bai Zhen-Yu Qi Guo-Zhen Hui Zhong Wang Overweight, obesity and meningioma risk: a meta-analysis.
description	<h4>Background and objectives</h4>Studies of the association between excess body weight and risk of meningioma have produced inconsistent results. Therefore, a meta-analysis of published studies was performed to better assess the association between meningioma and excess body weight.<h4>Methods</h4>A literature search was conducted in the PubMed and EMBASE databases without any limitations. The reference lists of identified articles were also screened for additional studies. The summary relative risks (RRs) and 95% confidence intervals (CI) were calculated using fixed- or random-effects models.<h4>Results</h4>A total of 6 studies provided risk estimates for overweight or obesity. Overall, the combined RRs were 1.12 (95% CI = 0.98-1.28) for overweight and 1.45 (95% CI = 1.26-1.67) for obesity. After stratification by gender, no significant association was observed for obese men (RR = 1.30, 95% CI = 0.64-2.62), while significant association was detected for obese women (RR = 1.46, 95% CI = 1.26-1.69). No substantial differences emerged across strata of study design and geographic areas.<h4>Conclusion</h4>The results of this meta-analysis suggest that obesity but not overweight is associated with an increased risk of meningioma. Due to the limited number of studies, further research is needed to confirm the association.
format	article
author	Chuan Shao Li-Ping Bai Zhen-Yu Qi Guo-Zhen Hui Zhong Wang
author_facet	Chuan Shao Li-Ping Bai Zhen-Yu Qi Guo-Zhen Hui Zhong Wang
author_sort	Chuan Shao
title	Overweight, obesity and meningioma risk: a meta-analysis.
title_short	Overweight, obesity and meningioma risk: a meta-analysis.
title_full	Overweight, obesity and meningioma risk: a meta-analysis.
title_fullStr	Overweight, obesity and meningioma risk: a meta-analysis.
title_full_unstemmed	Overweight, obesity and meningioma risk: a meta-analysis.
title_sort	overweight, obesity and meningioma risk: a meta-analysis.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/9713de80aa9843c3ab625325036ee351
work_keys_str_mv	AT chuanshao overweightobesityandmeningiomariskametaanalysis AT lipingbai overweightobesityandmeningiomariskametaanalysis AT zhenyuqi overweightobesityandmeningiomariskametaanalysis AT guozhenhui overweightobesityandmeningiomariskametaanalysis AT zhongwang overweightobesityandmeningiomariskametaanalysis
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Overweight, obesity and meningioma risk: a meta-analysis.

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