Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum
Dopamine D2 receptor activity in the nucleus accumbens is associated with regulation of motivated responding. Here the authors show that overexpression of D2 receptors specifically in ventral striatal projection neurons leads to an increase in the willingness to work by reducing inhibitory transmiss...
Saved in:
Main Authors: | Eduardo F. Gallo, Jozsef Meszaros, Jeremy D. Sherman, Muhammad O. Chohan, Eric Teboul, Claire S. Choi, Holly Moore, Jonathan A. Javitch, Christoph Kellendonk |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/9716d06b79b041318d69d2b9867976d1 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Ventral pallidum encodes relative reward value earlier and more robustly than nucleus accumbens
by: David Ottenheimer, et al.
Published: (2018) -
Opponent control of behavioral reinforcement by inhibitory and excitatory projections from the ventral pallidum
by: Lauren Faget, et al.
Published: (2018) -
Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
by: Carina Soares-Cunha, et al.
Published: (2016) -
Ventral pallidum neurons dynamically signal relative threat
by: Mahsa Moaddab, et al.
Published: (2021) -
Phasic dopamine release in the rat nucleus accumbens predicts approach and avoidance performance
by: Ronny N. Gentry, et al.
Published: (2016)