Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital
Background: Transfusion-transmissible infections are well-known global health challenges. The present study is proposed to investigate the seropositivity of anti-HIV1/2, anti-HCV, HBsAg, and anti-<i>T.pallidum</i> among volunteer blood donors of Kosti Obstetrics and Gynecology Hospital....
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/971f718f49ac41de9ecaae76c02cb3b2 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Background: Transfusion-transmissible infections are well-known global health challenges. The present study is proposed to investigate the seropositivity of anti-HIV1/2, anti-HCV, HBsAg, and anti-<i>T.pallidum</i> among volunteer blood donors of Kosti Obstetrics and Gynecology Hospital. Methods: Our study was conducted in a cross-sectional retrospective manner. The data of donors who attended Kosti Obstetrics and Gynecology Hospital throughout 2016 to 2018 were reviewed and retrieved manually from blood bank records. Results: Out of 8139 donors, 22.52% were seropositive for serological markers of TTIs and 1.67% were seropositive for at least two serological markers of TTIs. The overall seropositivity rate of anti-HIV1/2, HBsAg, anti-HCV, and anti-<i>T.pallidum</i> was 1.77%, 6.07%, 1.14%, and 11.87%, respectively (<i>p</i> < 0.000). Anti-<i>T.pallidum</i> was the most frequently detected (<i>p</i> < 0.05) marker across all study variables. TTIs seroprevalence was significantly (<i>p</i> < 0.05) varied according to the age, residence, occupations, and blood groups. Notably, there was a rising trend in the rate of anti-HIV1/2 and seropositivity for more than one marker with age (<i>p</i> < 0.000). Regionally, rural area residents had a higher rate of anti-HIV1/2 (2.20%), HBsAg (6.31%), anti-HCV (1.42%), anti-<i>T.pallidum</i> (18.38%), and multiple markers seropositivity (2.28%) compared to urban areas. Between occupations, the highest rate of anti-HIV1/2 (<i>p</i> = 0.483), HBsAg (<i>p</i> = 0.003), anti-HCV (<i>p</i> = 0.408), anti-<i>T.pallidum</i> (<i>p</i> < 0.000), and multiple markers seropositivity (<i>p</i> < 0.000) were detected in farmers. Regarding the screening, we also found that the frequency of anti-<i>T.pallidum</i> was significantly (<i>p</i> = 0.003) higher in donors who carry the AB+ve blood group, whereas anti-HCV (1.83%) was more frequent in donors carry O−ve blood group (<i>p</i> = 0.255). As seen, anti-<i>T.pallidum</i>+HBsAg was the most frequently (1.22%) co-occurring markers. In contrast, anti-<i>T.pallidum</i>+anti-HIV1/2+HBsAg was the lowest frequency one (<i>p</i> < 0.000). Conclusions: The study showed an alarming rate of TTIs, which suggests the requirement for comprehensive surveillance and health education programs. |
|---|