Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital

Background: Transfusion-transmissible infections are well-known global health challenges. The present study is proposed to investigate the seropositivity of anti-HIV1/2, anti-HCV, HBsAg, and anti-<i>T.pallidum</i> among volunteer blood donors of Kosti Obstetrics and Gynecology Hospital....

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Autores principales:	Babiker Saad Almugadam, Omer Mohammed Ali Ibrahim, Yousif Mousa Alobaid Ahmed
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	anti-HIV1/2 anti-HCV anti-<i>T.pallidum</i> HBsAg TTIs Medicine R
Acceso en línea:	https://doaj.org/article/971f718f49ac41de9ecaae76c02cb3b2
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spelling	oai:doaj.org-article:971f718f49ac41de9ecaae76c02cb3b22021-11-25T18:19:19ZSeroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital10.3390/medicines81100642305-6320https://doaj.org/article/971f718f49ac41de9ecaae76c02cb3b22021-10-01T00:00:00Zhttps://www.mdpi.com/2305-6320/8/11/64https://doaj.org/toc/2305-6320Background: Transfusion-transmissible infections are well-known global health challenges. The present study is proposed to investigate the seropositivity of anti-HIV1/2, anti-HCV, HBsAg, and anti-<i>T.pallidum</i> among volunteer blood donors of Kosti Obstetrics and Gynecology Hospital. Methods: Our study was conducted in a cross-sectional retrospective manner. The data of donors who attended Kosti Obstetrics and Gynecology Hospital throughout 2016 to 2018 were reviewed and retrieved manually from blood bank records. Results: Out of 8139 donors, 22.52% were seropositive for serological markers of TTIs and 1.67% were seropositive for at least two serological markers of TTIs. The overall seropositivity rate of anti-HIV1/2, HBsAg, anti-HCV, and anti-<i>T.pallidum</i> was 1.77%, 6.07%, 1.14%, and 11.87%, respectively (<i>p</i> < 0.000). Anti-<i>T.pallidum</i> was the most frequently detected (<i>p</i> < 0.05) marker across all study variables. TTIs seroprevalence was significantly (<i>p</i> < 0.05) varied according to the age, residence, occupations, and blood groups. Notably, there was a rising trend in the rate of anti-HIV1/2 and seropositivity for more than one marker with age (<i>p</i> < 0.000). Regionally, rural area residents had a higher rate of anti-HIV1/2 (2.20%), HBsAg (6.31%), anti-HCV (1.42%), anti-<i>T.pallidum</i> (18.38%), and multiple markers seropositivity (2.28%) compared to urban areas. Between occupations, the highest rate of anti-HIV1/2 (<i>p</i> = 0.483), HBsAg (<i>p</i> = 0.003), anti-HCV (<i>p</i> = 0.408), anti-<i>T.pallidum</i> (<i>p</i> < 0.000), and multiple markers seropositivity (<i>p</i> < 0.000) were detected in farmers. Regarding the screening, we also found that the frequency of anti-<i>T.pallidum</i> was significantly (<i>p</i> = 0.003) higher in donors who carry the AB+ve blood group, whereas anti-HCV (1.83%) was more frequent in donors carry O−ve blood group (<i>p</i> = 0.255). As seen, anti-<i>T.pallidum</i>+HBsAg was the most frequently (1.22%) co-occurring markers. In contrast, anti-<i>T.pallidum</i>+anti-HIV1/2+HBsAg was the lowest frequency one (<i>p</i> < 0.000). Conclusions: The study showed an alarming rate of TTIs, which suggests the requirement for comprehensive surveillance and health education programs.Babiker Saad AlmugadamOmer Mohammed Ali IbrahimYousif Mousa Alobaid AhmedMDPI AGarticleanti-HIV1/2anti-HCVanti-<i>T.pallidum</i>HBsAgTTIsMedicineRENMedicines, Vol 8, Iss 64, p 64 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	anti-HIV1/2 anti-HCV anti-<i>T.pallidum</i> HBsAg TTIs Medicine R
spellingShingle	anti-HIV1/2 anti-HCV anti-<i>T.pallidum</i> HBsAg TTIs Medicine R Babiker Saad Almugadam Omer Mohammed Ali Ibrahim Yousif Mousa Alobaid Ahmed Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital
description	Background: Transfusion-transmissible infections are well-known global health challenges. The present study is proposed to investigate the seropositivity of anti-HIV1/2, anti-HCV, HBsAg, and anti-<i>T.pallidum</i> among volunteer blood donors of Kosti Obstetrics and Gynecology Hospital. Methods: Our study was conducted in a cross-sectional retrospective manner. The data of donors who attended Kosti Obstetrics and Gynecology Hospital throughout 2016 to 2018 were reviewed and retrieved manually from blood bank records. Results: Out of 8139 donors, 22.52% were seropositive for serological markers of TTIs and 1.67% were seropositive for at least two serological markers of TTIs. The overall seropositivity rate of anti-HIV1/2, HBsAg, anti-HCV, and anti-<i>T.pallidum</i> was 1.77%, 6.07%, 1.14%, and 11.87%, respectively (<i>p</i> < 0.000). Anti-<i>T.pallidum</i> was the most frequently detected (<i>p</i> < 0.05) marker across all study variables. TTIs seroprevalence was significantly (<i>p</i> < 0.05) varied according to the age, residence, occupations, and blood groups. Notably, there was a rising trend in the rate of anti-HIV1/2 and seropositivity for more than one marker with age (<i>p</i> < 0.000). Regionally, rural area residents had a higher rate of anti-HIV1/2 (2.20%), HBsAg (6.31%), anti-HCV (1.42%), anti-<i>T.pallidum</i> (18.38%), and multiple markers seropositivity (2.28%) compared to urban areas. Between occupations, the highest rate of anti-HIV1/2 (<i>p</i> = 0.483), HBsAg (<i>p</i> = 0.003), anti-HCV (<i>p</i> = 0.408), anti-<i>T.pallidum</i> (<i>p</i> < 0.000), and multiple markers seropositivity (<i>p</i> < 0.000) were detected in farmers. Regarding the screening, we also found that the frequency of anti-<i>T.pallidum</i> was significantly (<i>p</i> = 0.003) higher in donors who carry the AB+ve blood group, whereas anti-HCV (1.83%) was more frequent in donors carry O−ve blood group (<i>p</i> = 0.255). As seen, anti-<i>T.pallidum</i>+HBsAg was the most frequently (1.22%) co-occurring markers. In contrast, anti-<i>T.pallidum</i>+anti-HIV1/2+HBsAg was the lowest frequency one (<i>p</i> < 0.000). Conclusions: The study showed an alarming rate of TTIs, which suggests the requirement for comprehensive surveillance and health education programs.
format	article
author	Babiker Saad Almugadam Omer Mohammed Ali Ibrahim Yousif Mousa Alobaid Ahmed
author_facet	Babiker Saad Almugadam Omer Mohammed Ali Ibrahim Yousif Mousa Alobaid Ahmed
author_sort	Babiker Saad Almugadam
title	Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital
title_short	Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital
title_full	Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital
title_fullStr	Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital
title_full_unstemmed	Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital
title_sort	seroprevalence of the serological markers of transfusion-transmissible infections among volunteer blood donors of kosti obstetrics and gynecology hospital
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/971f718f49ac41de9ecaae76c02cb3b2
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Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital

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