Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases
The development of brain metastases is a lethal yet poorly understood event in the evolution of many cancers. Here, the authors perform whole-genome and whole-exome sequencing on matched normal, primary and metastatic tissue samples to explore the genomic features of brain metastases in colorectal c...
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Autores principales: | Jing Sun, Cheng Wang, Yi Zhang, Lingyan Xu, Weijia Fang, Yuping Zhu, Yi Zheng, Xiaofeng Chen, Xiju Xie, Xinhua Hu, Weidong Hu, Jingyu Zheng, Ping Li, Jian Yu, Zhu Mei, Xiaomin Cai, Biao Wang, Zhibin Hu, Yongqian Shu, Hongbing Shen, Yanhong Gu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/971f843531b644688afff75b88f27399 |
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