Functional mapping of brain synapses by the enriching activity-marker SynaptoZip

Visualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.

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Detalles Bibliográficos
Autores principales: Mattia Ferro, Jacopo Lamanna, Maddalena Ripamonti, Gabriella Racchetti, Alessandro Arena, Sara Spadini, Giovanni Montesano, Riccardo Cortese, Vincenzo Zimarino, Antonio Malgaroli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/972547f89abe41b0ab123373ee104007
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Sumario:Visualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.