MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells
Abstract MZB1 is an endoplasmic reticulum (ER)-resident protein that plays an important role in the humoral immune response by enhancing the interaction of the μ immunoglobulin (Ig) heavy chain with the chaperone GRP94 and by augmenting the secretion of IgM. Here, we show that MZB1 is also expressed...
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Autores principales: | Tanya Kapoor, Mauro Corrado, Erika L. Pearce, Edward J. Pearce, Rudolf Grosschedl |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Acceso en línea: | https://doaj.org/article/972697e64b8a4a0083614fad217f537c |
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