Quinacrine-CASIN combination overcomes chemoresistance in human acute lymphoid leukemia

Quinacrine-CASIN combination overcomes chemoresistance in human acute lymphoid leukemia

Chemoresistance and relapse are main limitations in the treatment of acute lymphoblastic leukemia (ALL). Here, the authors identify Quinacrine (QC) as a sensitizer for Cytarabine (AraC) and establish a QC-CASIN regimen to improve leukemia eradication in ALL.

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Detalles Bibliográficos
Autores principales: Limei Wu, Srinivas Chatla, Qiqi Lin, Fabliha Ahmed Chowdhury, Werner Geldenhuys, Wei Du
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/97269be323ee4237991e7229e073c7fe
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